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On this month’s MedEvidence radio episode, Doctors Michael Koren, MD, Matthew Todd Braddock, DO, Jackson Downey, MD, Albert Lopez, DO and WSOS Radio Host Kevin Geddings discuss NASH, Fatty Liver, and Fibroscans.

This month’s MedEvidence! Radio will answer:

  • What is NASH?
  • What are the stages of NASH?
  • How do you treat NASH?
  • Is NASH reversible?
  • Is NASH related to cholesterol problems?

MedEvidence! Radio is a monthly live broadcast from WSOS 103.9 FM / 1170 AM with Kevin Geddings from St. Augustine, Florida. Dr. Michael Koren is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals.  Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital/Memorial Sloan-Kettering Cancer Center/Cornell Medical Center.  On a personal note, Dr. Koren has a lifelong interest in history, technology, Public Health, and music. He has written two musical plays.


Listen to the full episode here:




Clinical Trials Day is celebrated around the world in May to recognize the day that James Lind started what is often considered the first clinical trial aboard a ship on May 20, 1747.

Here’s the story…

Also included in this month’s MedEvidence! Radio

  • Why we do Clinical Trials
  • Phases of Clinical Trials
  • Why you may want to participate in clinical trials

MedEvidence! Radio is a monthly live broadcast from WSOS 103.9 FM / 1170 AM with Kevin Geddings from St. Augustine, Florida. Dr. Michael Koren is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals.  Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital/Memorial Sloan-Kettering Cancer Center/Cornell Medical Center.  On a personal note, Dr. Koren has a life-long interest in history, technology, Public Health, and music. He has written two musical plays.


Listen to the full episode here:




This week’s MedEvidence podcast is on Medical Marijuana. Meet Dr. Charlie Booras, former Principal Investigator at Jacksonville Center of Clinical Research, and Baptist Primary Care physician who grew his practice into Booras MD as a tribute to his father after treating his ALS with medical cannabis as a medication. Dr. Michael Koren and Dr. Booras dive into the scientific basis for the efficacy of medical cannabis.

You will learn:

        • Florida Medical Marijuana Law and Process
        • THC vs. CBD
        • Health Benefits for Medical Marijuana
        • History of Marijuana
        • Learn more about Clinical Research
        • Learn more about BoorasMD

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.


Prefer to listen to the podcast without video? You can do that below!






This week’s MedEvidence podcast is the second episode in a two-part series on Liquid Biopsy.

In this 24-minute episode Doctors, Michael Koren and Bharat Misra discuss liquid biopsy usage now & in the future of medical evaluations.

You will learn:

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Bharat Misra is the Medical Director of ENCORE Borland Groover Clinical Research and has been a Principal Investigator of numerous clinical trials. He also serves on the board of directors at Memorial Hospital and Jacksonville Center for Clinical Research in Jacksonville, Florida. He completed his residency in internal medicine and fellowship in gastroenterology at the Nassau University Medical Center, State University of New York, and his Bachelor of Medicine and Bachelor of Surgery from Gandhi Medical College in India.


Prefer to listen to the podcast without video? You can do that below!





This week’s MedEvidence podcast is a two-part series on Liquid Biopsy: What is it & Do I Need One?

In this 22-minute episode Doctors, Michael Koren and Bharat Misra explain liquid biopsies and conditions that are subject to evaluations with liquid biopsies.

You will learn

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Bharat Misra is the Medical Director of ENCORE Borland Groover Clinical Research and has been a Principal Investigator of numerous clinical trials. He also serves on the board of directors at Memorial Hospital and Jacksonville Center for Clinical Research in Jacksonville, Florida. He completed his residency in internal medicine and fellowship in gastroenterology at the Nassau University Medical Center, State University of New York, and his Bachelor of Medicine and Bachelor of Surgery from Gandhi Medical College in India.


Prefer to listen to the podcast without video? You can do that below!





“What New with the Flu?”  Dr. Michael Koren, Dr. Victoria Helow, and Michelle McCormick discuss Flu and COVID.

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Victoria Helow, is a well-respected pediatrician, clinical research investigator at ENCORE Research Group, and practicing emergency room physician.


Prefer to listen to the podcast without video? You can do that below!





Wrapping up this month’s MedEvidence! podcast series on “What to do after a Heart Attack or Stroke?”  Doctors, Michael Koren and Albert Lopez, DO discuss treatments, medications, and clinical research you need to know as a post-heart event patient.

You will learn:

  • Treatment therapies to use after a heart attack or stroke
  • What is Lp(a)
  • Male vs Female Symptoms
  • Cardiovascular Disease Research

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Albert Lopez, DO practices Internal Medicine with Millennium Physician Group in Jacksonville, Florida. He is also a Principal Investigator with ENCORE Research Group specializing in lipid clinical trials. Dr. Lopez, DO completed his residency at the University of Pennsylvania and his Doctor of Osteopathic Medicine at Nova Southeastern University in Miami, Florida. He is known as one of the earliest evidence-based physicians in Jacksonville utilizing nutrition and lifestyle for disease prevention.
I believe in “N” of one” because “N of one” is about the patient. If it is not about the patient, then it is about nothing. – Dr. Albert Lopez, DO


Prefer to listen to the podcast without video? You can do that below!





This month’s MedEvidence! podcast is a three-part series on “What to do after a Heart Attack or Stroke?” In the first MedEvidence segment we established that people who have had either a heart attack or stroke have a high risk for a repeat procedure or event. We also discussed knowing who’s on your Heart Health Team, PCP, specialist, and family. What’s abnormal, normal, and what to do when symptoms last greater than 20 minutes? In this 15-minute episode, Doctors, Michael Koren and Albert Lopez DO discuss the Risk Factors You Need to know for your heart health.

You will learn:

      • What modifiable risk factors are
      • What non-modifiable risk factors are
      •  What you can do to help your risk factors
      • How clinical trials and research find other drug benefits
      • How to be involved in a clinical trial

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Albert Lopez, DO practices Internal Medicine with Millennium Physician Group in Jacksonville, Florida. He is also a Principal Investigator with ENCORE Research Group specializing in lipid clinical trials. Dr. Lopez, DO completed his residency at the University of Pennsylvania and his Doctor of Osteopathic Medicine at Nova Southeastern University in Miami, Florida. He is known as one of the earliest evidence-based physicians in Jacksonville utilizing nutrition and lifestyle for disease prevention.
I believe in “N” of one” because “N of one” is about the patient. If it is not about the patient, then it is about nothing. – Dr. Albert Lopez, DO


Prefer to listen to the podcast without video? You can do that below!





This MedEvidence! podcast is a three-part series on “What to do after a Heart Attack or Stroke?” In this episode, Doctors, Michael Koren and Albert Lopez, DO help you identify your heart health team.

You will learn:

    • Who do I call if I think I’m having a heart attack?
    • What are my risks for another event?
    • How can my family help?
    • How to find a clinical trial

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Albert Lopez, DO practices Internal Medicine with Millennium Physician Group in Jacksonville, Florida. He is also a Principal Investigator with ENCORE Research Group specializing in lipid clinical trials. Dr. Lopez, DO completed his residency at the University of Pennsylvania and his Doctor of Osteopathic Medicine at Nova Southeastern University in Miami, Florida. He is known as one of the earliest evidence-based physicians in Jacksonville utilizing nutrition and lifestyle for disease prevention.
I believe in “N” of one” because “N of one” is about the patient. If it is not about the patient, then it is about nothing. – Dr. Albert Lopez, DO


Prefer to listen to the podcast without video? You can do that below!





In this final 30-minute episode Doctors, Michael Koren and Bharat Misra dive into new treatments in clinical trials for Fatty Liver Disease and NASH.

You will learn

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Bharat Misra is the Medical Director of ENCORE Borland Groover Clinical Research and has been a Principal Investigator of numerous clinical trials. He also serves on the board of directors at Memorial Hospital and Jacksonville Center for Clinical Research in Jacksonville, Florida. He completed his residency in internal medicine and fellowship in gastroenterology at the Nassau University Medical Center, State University of New York, and his Bachelor of Medicine and Bachelor of Surgery from Gandhi Medical College in India.


Prefer to listen to the podcast without video? You can do that below!





This month’s MedEvidence! Hour is a three-part series on You Cannot Live without Your Liver.   In this 14-minute Part 2 episode Doctors, Michael Koren and Bharat Misra answer your questions on Fibroscans.

  • Who should receive a Fibroscan
  • How often should I get a Fibroscan
  • Should I ask my primary doctor for a Fibroscan
  • Liver Biopsy vs. Fibroscan
  • Insurance and Fibroscan
  • What should I do after my Fibroscan
  • How to find a free Fibroscan

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Bharat Misra is the Medical Director of ENCORE Borland Groover Clinical Research and has been a Principal Investigator of numerous clinical trials. He also serves on the board of directors at Memorial Hospital and Jacksonville Center for Clinical Research in Jacksonville, Florida. He completed his residency in internal medicine and fellowship in gastroenterology at the Nassau University Medical Center, State University of New York, and his Bachelor of Medicine and Bachelor of Surgery from Gandhi Medical College in India.


Prefer to listen to the podcast without video? You can do that below!





This month’s MedEvidence is a three-part series on the liver.   In this 12-minute episode Doctors, Michael Koren and Bharat Misra discuss technologies to diagnose dysfunctions of the liver.

You will learn:

  • Technologies in clinical research
  • What a fibroscan is
  • Why your doctor may not be offering you a fibroscan
  • Liver biopsy vs. MRI vs. fibroscan

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.

Dr. Bharat Misra is the Medical Director of ENCORE Borland Groover Clinical Research and has been a Principal Investigator of numerous clinical trials. He also serves on the board of directors at Memorial Hospital and Jacksonville Center for Clinical Research in Jacksonville, Florida. He completed his residency in internal medicine and fellowship in gastroenterology at the Nassau University Medical Center, State University of New York, and his Bachelor of Medicine and Bachelor of Surgery from Gandhi Medical College in India.


Prefer to listen to the podcast without video? You can do that below!





In this episode, Dr. Michael Koren and Michelle McCormick wrap up their discussion on how clinical trials find the truth as well as truth vs. faith and the conclusion of lady tasting tea. Could she actually tell whether the milk or tea was put in first?

Dr. Michael Koren is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.


Prefer to listen to the podcast without video? You can do that below!





In this episode, Dr. Michael Koren and Michelle McCormick walk through the history of Clinical Trials. From Biblical stories of Daniel through the smallpox pandemic to our present COVID pandemic. How far have we come and where do we go from here?

Some of what you will learn:

  • History of Clinical Research
    • Daniel and King Nebuchadnezzar
    • Newgate Prison
    • Cotton Mather & Onesimus
  • Current Vaccine Trials
    • Chickenpox
    • Shingles
    • Covid
    • Flu
    • RSV
  • Future of COVID

Dr. Michael Koren is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.


Prefer to listen to the podcast without video? You can do that below!





In this second episode, Dr. Michael Koren, New York Central High School alumni, and Michelle McCormick take us back to high school minus having that awkward conversation about asking your date to prom.  Listen to find out what your high school classes have to do with clinical trials.

Some of what you will learn:

  • What makes a good hypothesis
  • Statistical concepts
  • Statistical methods involved in carrying out a study
  • The vocabulary of clinical research
  • History of clinical research
    • Newgate Prison
    • Daniel and King Nebuchadnezzar
    • Pepsi vs. Coke

Dr. Michael Koren is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.


Prefer to listen to the podcast without video? You can do that below!





In a four-part series on What are Clinical Trials & Why are they important, in this first episode Dr. Michael Koren and Michelle McCormick talk about The Science of Clinical Trials, What makes a good Clinical Trial, good?

What do these things have in common?

  • R.A. Fisher
  • Lady Tasting Tea
  • Truth vs Faith
  • Experiments
  • Clinical Trials

Dr. Michael Koren, is a practicing cardiologist and CEO at ENCORE Research Group. He has been the principal investigator of 2000+ clinical trials while being published in the most prestigious medical journals. Dr. Koren received his medical degree cum laude at Harvard Medical School and completed his residency in internal medicine with a fellowship in cardiology at New York Hospital / Memorial Sloan-Kettering Cancer Center/ Cornell Medical Center.


Prefer to listen to the podcast without video? You can do that below!





In the final episode of Kicking the Nicotine Habit, It’s a Brain Thing. The MedEvidence! doctors roll out the clinical trials on Cytisinicline, an approved therapy in central and Eastern West Europe for the past 20 years.

This month Dr. Michael Koren and Michelle McCormick talk with Dr. Mitchell Rothstein, a clinical Pulmonary and Sleep Medicine physician for 30 years in the Jacksonville, Florida area.  Dr. Rothstein is the Medical Director of the Phase 1 unit at Jacksonville Center for Clinical Research.

Inside this episode:

  • Cytisinicline
  • Alpha4beta2 Nicotine Receptor
  • Clinical Trials to help quit smoking

Prefer to listen to the podcast without video? You can do that below!





Part 3 in a 4 part series on Kicking the Nicotine Habit, It’s a Brain Thing. The MedEvidence doctors continue their discussion on smoking while diving into nicotine replacement therapies.

This month Dr. Michael Koren and Michelle McCormick talk with Dr. Mitchell Rothstein, a clinical Pulmonary and Sleep Medicine physician for 30 years in the Jacksonville, Florida area.  Dr. Rothstein is the Medical Director of the Phase 1 unit at Jacksonville Center for Clinical Research.

Inside this episode:

  • Nicotine Replacement Therapies
  • Quit smoking medications
  • E-cigarettes & Vaping
  • IQOS – heated tobacco products

Prefer to listen to the podcast without video? You can do that below!





Part 2 in a 4 part series on Kicking the Nicotine Habit, It’s a Brain Thing. Today the doctors dive into the behavioral habits of smoking and give you 5 strategies you can start NOW.

This month Dr. Michael Koren and Michelle McCormick talk with Dr. Mitchell Rothstein, a clinical Pulmonary and Sleep Medicine physician for 30 years in the Jacksonville, Florida area.  Dr. Rothstein is the Medical Director of the Phase 1 unit at Jacksonville Center for Clinical Research.

Inside this episode:

  • Do you want to stop smoking?
  • How do you get to that point?
  • Behavioral Modification strategies
  • 5 Things you can do today to stop smoking

Prefer to listen to the podcast without video? You can do that below!





Part 1 in a 4 part series on Kicking the Nicotine Habit, It’s a Brain Thing.

This month Dr. Michael Koren and Michelle McCormick talk with Dr. Mitchell Rothstein, a clinical Pulmonary and Sleep Medicine physician for 30 years in the Jacksonville, Florida area.  Dr. Rothstein is the Medical Director of the Phase 1 unit at Jacksonville Center for Clinical Research.

Inside this episode:

  • What makes smoking harmful?
  • What makes smoking so addictive?
  • Preventable form of Cardiovascular factors

Prefer to listen to the podcast without video? You can do that below!





This month’s MedEvidence guest, Dr. Steven Toenjes, MD, a board-certified neurologist, former staff neurologist in the U.S. Navy, and an award-winning director of neurology residents at the Uniformed Services University of Health Sciences and decorated Navy veteran, joins Dr. Michael Koren and Michelle McCormick to discuss the future of Alzheimer’s research and what your gut has to do with Alzheimer’s.


Prefer to listen to the podcast without video? You can do that below!





What are all the hullabaloos about Aduhelm, the first new Alzheimer’s drug approval since 2003? This month’s MedEvidence guest, Dr. Steven Toenjes, MD, a board-certified neurologist, former staff neurologist in the U.S. Navy, and an award-winning director of neurology residents at the Uniformed Services University of Health Sciences and decorated Navy veteran joins Dr. Michael Koren and Michelle McCormick to discuss the first new Alzheimer’s drug approval since 2003 and the controversy over FDA’s approval of Biogen’s Aducanumab (Aduhelm).


Prefer to listen to the podcast without video? You can do that below!





In Part 2: Is it Alzheimer’s or Something Else? Drs. Toenjes and Koren begin by answering the popular question, “When do you know something is wrong? Followed by explaining amyloid proteins, DNA structure, Alzheimer’s therapy, and the research behind it.

Dr. Steven Toenjes, MD, a board-certified neurologist, former staff neurologist in the U.S. Navy, and an award-winning director of neurology residents at the Uniformed Services University of Health Sciences and decorated Navy veteran, joins Dr. Michael Koren and Michelle McCormick to discuss Alzheimer’s disease in a four-part series.


Prefer to listen to the podcast without video? You can do that below!





This month’s MedEvidence guest, Dr. Steven Toenjes, MD, a board-certified neurologist, former staff neurologist in the U.S. Navy, and an award-winning director of neurology residents at the Uniformed Services University of Health Sciences and decorated Navy veteran joins Dr. Michael Koren and Michelle McCormick to discuss Alzheimer’s disease in a four-part series.

With over six million Americans believed to have Alzheimer’s disease and the sixth leading cause of death in the United States, MedEvidence breaks down Dementia vs. Alzheimer’s, including diagnosis and treatments.


Prefer to listen to the podcast without video? You can do that below!





In this final episode on longevity, Dr. Michael Koren, Dr. Victoria Helow, and Michelle McCormick talk about medical research and apply its wisdom to maximize a healthy lifestyle. Topics discussed:

  • Aspirin: Doses, Purposes & Populations
  • Types of anti-inflammatories
  • Importance of Cholesterol numbers
  • RNA Technology
  • Viruses
  • Vaccines
  • Hugging vs. Handshake
  • Becoming Part of Advancing Science

Related articles:


Prefer to listen to the podcast without video? You can do that below!





What is the formula to living longer? In this third episode in our four-part series Dr. Michael Koren, Dr. Victoria Helow, and Michelle McCormick apply medical research to fish, nuts, sex, sunscreen, and more.

Related articles:


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Can medical research help us live longer? In this four-part series Dr. Michael Koren, Dr. Victoria Helow, and Michelle McCormick discuss the relevant medical evidence and apply its wisdom to discover the secrets to longevity.

Related articles:


Prefer to listen to the podcast without video? You can do that below!





Can medical research help us live longer? In this four-part series Dr. Michael Koren, Dr. Victoria Helow, and Michelle McCormick discuss the relevant medical evidence and apply its wisdom to discover the secrets to longevity.

Related articles:


Prefer to listen to the podcast without video? You can do that below!



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