Overweight/Obesity Research

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Overweight/Obesity Research



Click on the drop-down below to see the criteria for each location. 

Or sign up at the bottom of this page, and our office will call you!


  • Crystal River – Study (SYNCHRONIZE)
  • Jacksonville Westside – Study (SYNCHRONIZE)
  • Jacksonville (University)- Study (SUSTAIN OPTIMIZE)
  • Jacksonville (University) – Study (REVITALIZE)
  • Inverness – Study (ACHIEVE 4)
Crystal River – Study (SYNCHRONIZE)

Overweight With Other Conditions

Nature Coast Clinical Research – Crystal River is conducting a research study that will evaluate the effect of an investigational weight loss drug on cardiovascular safety in people who are overweight or obese.

Obesity is widespread, difficult to manage, and can be unhealthy. It can increase cardiovascular risks, including chances of stroke, heart attack, and high blood pressure. Multiple signals in the body may change with obesity, making weight loss difficult. Medications that target these signaling pathways are needed to help fight this increasing epidemic, and clinical trials are needed to investigate potential solutions.

You may be eligible to participate if you:

  • Are 18+ years old
  • Have a BMI >27 with any of the following (A and/or B)
    • A. Have Cardiovascular Disease (CVD), including any of the following:
        • Heart failure
        • Coronary artery disease (CAD)
        • Previous heart attack
        • Previous stroke (ischemic or hemorrhagic)
        • Previous revascularization procedure
        • Stent(s)
        • Peripheral artery disease
    • B. Have a BMI >30 with Chronic Kidney Disease (CKD)

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost. Compensation for time and travel may be available. No health insurance is required to participate.

For more information call

(352) 563-1865

Or sign up below, and our friendly staff will call you!

Jacksonville Westside – Study (SYNCHRONIZE)

Overweight With Other Conditions

Westside Center for Clinical Research is conducting a research study that will evaluate the effect of an investigational weight loss drug on cardiovascular safety in people who are overweight or obese.

Obesity is widespread, difficult to manage, and can be unhealthy. It can increase cardiovascular risks, including chances of stroke, heart attack, and high blood pressure. Multiple signals in the body may change with obesity, making weight loss difficult. Medications that target these signaling pathways are needed to help fight this increasing epidemic, and clinical trials are needed to investigate potential solutions.

You may be eligible to participate if you:

  • Are 18+ years old
  • Have a BMI >27 with any of the following (A and/or B)
    • A. Have Cardiovascular Disease (CVD), including any of the following:
        • Heart failure
        • Coronary artery disease (CAD)
        • Previous heart attack
        • Previous stroke (ischemic or hemorrhagic)
        • Previous revascularization procedure
        • Stent(s)
        • Peripheral artery disease
    • B. Have a BMI >30 with Chronic Kidney Disease (CKD)

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost. Compensation for time and travel may be available. No health insurance is required to participate.

For more information call

(904) 693-1490

Or sign up below, and our friendly staff will call you!

Jacksonville (University)- Study (SUSTAIN OPTIMIZE)

Diabetes Research

We are conducting a research study for people with type 2 diabetes who are currently taking insulin glargine (ex: Lantus Solostar) and metformin. This research study will evaluate the effectiveness and safety of using semaglutide once weekly as an add-on treatment.

You may be eligible if you:

  • Are 18 or older
  • Are diagnosed with type 2 diabetes
  • Have a BMI of 25 or greater
  • Are taking daily metformin ≥1500 mg or maximally tolerated dose
  • Are taking once-daily insulin glargine (ex: Lantus Solostar) < 40 units per day

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive all study-related investigational drug, procedures, and medical exams at no cost, as well as a stipend for time and travel. No health insurance is required to participate.

For more information call

(904) 730-0166

Or sign up below, and our office will call you!

Jacksonville (University) – Study (REVITALIZE)
Inverness – Study (ACHIEVE 4)

Type 2 Diabetes and Increased Risk for Heart Disease or Stroke

Type 2 diabetes is frequently associated with coexisting conditions such as increased weight, hypertension, and increased blood lipoprotein (fat/cholesterol) concentrations. People with type 2 diabetes have a higher risk for cardiovascular disease. Global studies show approximately a third of individuals with type 2 diabetes have cardiovascular disease.

We are conducting a research study that will be comparing a new investigational medication with insulin therapy for people with type 2 diabetes and excess weight who are at risk for heart disease or stroke.

You may be eligible if you:

  • Are at least 18 years of age
  • Have a BMI of 25 or higher
  • Have type 2 diabetes with an HbA1c between 7 and 10.5
  • Are taking at least one oral medication for diabetes
  • Have or are at risk for heart disease, stroke, or other blood vessel diseases, or have kidney disease

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

For more information call

(352) 341-2100

Or sign up below, and our friendly staff will call you!



This research is enrolling at:


Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



Westside Center for Clinical Research
810 Lane Avenue South
Jacksonville, FL 32205
(904) 693-1490



Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 563-1865



Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



BELOW ARE HIDDEN ROWS

Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway
Suite D, 2nd Floor Fleming Island, FL 32003
(904) 621-0390



Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086

(904) 209-0043



ENCORE Borland Groover Clinical Research
4800 Belfort Road, Suite 301
Jacksonville, FL 32256
(904) 680-0871



Westside Center for Clinical Research
810 Lane Avenue South
Jacksonville, FL 32205
(904) 693-1490



Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865



Learn More

If you want us to contact you about this research study call (904) 730-0166 or sign up below!

Category
Crystal River, Jacksonville (University Blvd.), Jacksonville (Westside)
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As a proven clinical research organization, we take every precaution to ensure the safety of and maximize the value for our research volunteers. Qualified doctors, nurses and study coordinators on staff provide support and care throughout the research trial. Participation is always voluntary. We appreciate the time and effort that research volunteers bring to this important process.

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