Cardiovascular Disease

Do you or someone you know have Cardiovascular Disease?
Qualified volunteers may receive at no cost:
-
Investigational medications
-
Study-related medical care from a qualified doctor
-
Possible compensation for time and travel
No health insurance is required to participate in our studies.
View the criteria for each location by clicking the dropdown below, or sign up at the bottom, and our team will contact you directly.
- Fleming Island: Atherosclerotic Cardiovascular Disease (ASCVD)
- Jacksonville (University) – Study (JAGUAR)
- Jacksonville: University Blvd – ASCVD/CVOT
- Jacksonville: University Blvd – Moderate Calcific Aortic Valve Stenosis
- Jacksonville: Westside – Atherosclerotic Cardiovascular Disease (ASCVD)
- Jacksonville: Westside – Hypertension
- St. Augustine – Atherosclerotic Cardiovascular Disease (ASCVD)
- St. Augustine – Moderate Calcific Aortic Valve Stenosis
- St. Augustine – Study (MARITIME-ASCVD)

Join a Research Study for Cardiovascular Disease!
To qualify, you must:
- Be 18 years or older
- Have experienced at least one of the following Cardiovascular events:
- A Heart Attack
- A Large Artery Ischemic Stroke within the last year
- Revascularization procedure due to symptomatic Peripheral Artery Disease
- Have at least one of the following conditions/factors:
- Type 2 Diabetes
- Aged 65 or older
- Multivessel Disease
- Additional previous Heart Attack
- Stage A, B or C Chronic Kidney Disease (CKD)
- Lower extremity revascularization due to poor circulation or to treat a large vessel ischemic stroke
- On a stable dose of maximum-tolerated Statin for at least a month
Please note additional criteria will apply
Study Location: Fleming Island, FL
What is an abdominal aortic aneurysm?
An abdominal aortic aneurysm (AAA) is a bulge in the aorta (the main artery leaving the heart) caused by a weakening in the artery wall. If left untreated, this bulge may continue to grow and possibly rupture (break open), causing serious internal bleeding.
If you or someone you know has AAA, you may qualify for our research study.
See if you qualify today!
Call 904-230-0166

Join a Research Study for Cardiovascular Disease!
To qualify, you must:
- Be 18 years or older
- Have experienced at least one of the following Cardiovascular events:
- A Heart Attack
- A Large Artery Ischemic Stroke within the last year
- Revascularization procedure due to symptomatic Peripheral Artery Disease
- Have at least one of the following conditions/factors:
- Type 2 Diabetes
- Aged 65 or older
- Multivessel Disease
- Additional previous Heart Attack
- Stage A, B or C Chronic Kidney Disease (CKD)
- Lower extremity revascularization due to poor circulation or to treat a large vessel ischemic stroke
- On a stable dose of maximum-tolerated Statin for at least a month
Please note additional criteria will apply
Study Location: Jacksonville, FL
KAR-ATA-301 KATALYST-AV
     Purpose of the Study:
- This study is testing an investigational medication to:
- Slow the buildup of calcium on the aortic valve
- Slow worsening of aortic valve narrowing
- Improve heart function and exercise ability
    Who Can Join This Study:
- You may be able to take part if you:
- Are 50 years or older
- Have moderate calcific aortic valve stenosis (CAVS)
- Have not had prior aortic valve replacement or repair
- Have heart function above a certain level
- Are able to complete study testing (like exercise testing)
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New Cardiovascular Research Study Now EnrollingÂ
Westside Center for Clinical Research is currently seeking volunteers for a new clinical research study focused on Atherosclerotic Cardiovascular Disease (ASCVD). This study is designed for adults who have experienced a recent cardiovascular event and are currently taking a statin medication.Â
About This StudyÂ
Cardiovascular disease remains one of the leading causes of serious health complications worldwide. This research study is evaluating potential approaches that may help improve outcomes for people living with ASCVD who are already receiving statin therapy.Â
Researchers are looking to better understand how new therapies may support individuals who have experienced significant cardiovascular events.Â
Your participation could help researchers learn more about improving heart health and preventing future complications.Â
Who May QualifyÂ
You may be eligible to participate if you:Â
- Are an adult 18 years of age or older Â
- Have experienced one of the following cardiovascular events within the last year:Â
- Heart attackÂ
- Large artery ischemic strokeÂ
- A revascularization procedure due to symptomatic peripheral artery diseaseÂ
- Are currently taking a stable dose of a statin medicationÂ
- Are on a maximum tolerated dose of statin therapyÂ

New Cardiovascular Research Study Now EnrollingÂ
Westside Center for Clinical Research is looking at how certain medications can help people with kidney disease or type 2 diabetes (T2DM). The research focuses on how these medicines may:Â
- Slow the progression of kidney diseaseÂ
- Reduce the risk of heart-related problemsÂ
- Help manage blood sugar levels in children, teens, and adults with T2DMÂ
Who Can ParticipateÂ
- Adults with chronic kidney disease (CKD), with or without diabetesÂ
- Children and adolescents with type 2 diabetes, especially if they are taking or cannot tolerate metformin or insulin

New Cardiovascular Research Study Now EnrollingÂ
St. Johns Center for Clinical Research are currently seeking volunteers for a new clinical research study focused on Atherosclerotic Cardiovascular Disease (ASCVD). This study is designed for adults who have experienced a recent cardiovascular event and are currently taking a statin medication.Â
About This StudyÂ
Cardiovascular disease remains one of the leading causes of serious health complications worldwide. This research study is evaluating potential approaches that may help improve outcomes for people living with ASCVD who are already receiving statin therapy.Â
Researchers are looking to better understand how new therapies may support individuals who have experienced significant cardiovascular events.Â
Your participation could help researchers learn more about improving heart health and preventing future complications.Â
Who May QualifyÂ
You may be eligible to participate if you:Â
- Are an adult 18 years of age or older Â
- Have experienced one of the following cardiovascular events within the last year:Â
- Heart attackÂ
- Large artery ischemic strokeÂ
- A revascularization procedure due to symptomatic peripheral artery diseaseÂ
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Purpose of the Study:
- This study is testing an investigational medication to:
- Â Slow the buildup of calcium on the aortic valve
- Slow worsening of aortic valve narrowing
- Improve heart function and exercise ability
Â
Who Can Join This Study?
- You may be able to take part if you:
- Are 50 years or older
- Have moderate calcific aortic valve stenosis (CAVS)
- Have not had prior aortic valve replacement or repair
- Have heart function above a certain level
- Are able to complete study testing (like exercise testing)

45+ with a History of Heart Attack or Stroke?Â
You may qualify for a new research study at St. John’s Center for Clinical Research focused on improving the future of cardiovascular care.Â
If you’re living with heart disease, prior heart attack, or stroke, and are also managing weight challenges, this study may be an opportunity to explore new approaches to treatment—while helping advance medical research.Â
About the StudyÂ
This cardiovascular research study is designed for adults who have experienced a heart attack or stroke and are currently overweight or obese.Â
Researchers are working to better understand how to improve outcomes and develop future treatment options for individuals with cardiovascular conditions.Â
By participating, you’ll play an important role in helping advance heart health research for future generations.Â
 Who May Qualify?Â
You may be eligible to participate if you:Â
✅ Are 45 years of age or older
✅ Have a history of heart attack or stroke
✅ Have a BMI of 27 or higher(overweight or obese) Â
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This research study is enrolling at:
Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway
Suite D, 2nd Floor Fleming Island, FL 32003
(904) 621-0390
Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166
St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086
(904) 209-0043
Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865
Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway
Suite D, 2nd Floor Fleming Island, FL 32003
(904) 621-0390
Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166
St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086
(904) 209-0043
ENCORE Borland Groover Clinical Research
4800 Belfort Road, Suite 301
Jacksonville, FL 32256
(904) 680-0871
Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100
Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865
Sign up below to join our research studies and make a difference!
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