Heart Failure Clinical Research

You may be eligible if you:

• Are 30-85 years old (inclusive)
• Have heart failure
• Have a reduced ejection fraction (≤35%)

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

For more information call

(352) 341-2100

Or sign up below, and our friendly staff will call you!

Heart Failure Research

With heart failure, the heart becomes incapable of pumping enough blood to meet the needs of the entire body. This condition affects millions of Americans and can limit how much ordinary physical activity people can perform. Despite long-term trends, recent data shows that the rate of heart failure is on the rise for many Americans. Clinical research is needed to address this growing concern. 

Jacksonville Center for Clinical Research is conducting a research study for volunteers to evaluate an investigational medication for people with Heart Failure and a reduced ejection fraction. 

 You may be eligible to participate if you: 

• Are 18+ years old 

• Have symptoms of heart failure 

• • Shortness of breath 

• • Fatigue 

• • Chest pain 

• Have an Ejection Fraction (LVEF) less than 50% 

• Have been on stable ACE inhibitor, ARB medication, or Entresto for at least 1 month 

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate. 

For more information call 

(904) 730-0166

Or sign up below, and our friendly staff will call you!

BOIN 1378-0018 HFrEF (MJK)

Purpose of the Study:

This study is testing whether vicadrostat plus empagliflozin can help people with chronic heart failure whose heart pumping function is reduced (LVEF less than 40%). Participants must have been diagnosed with heart failure for at least 3 months.

You may be able to join this study if you:

• Are 18 years of age or older
• Have had heart failure for at least 3 months
• Have a weakened heart pumping function (LVEF less than 40%)
• Have ongoing heart failure symptoms
• Are receiving standard treatment for heart failure

You may not be able to join this study if you:

• Take certain medications that are not allowed during the study
• Recently had a serious heart-related event, such as a heart attack or stroke
• Recently had major surgery or a major heart procedure
• Have severe worsening of heart failure requiring intensive treatment
• Have had a heart transplant, are waiting for one, or use a heart assist device
• Have certain uncommon heart diseases or recent inflammation of the heart

Additional eligibility criteria apply.

Why participate?

• Help advance research in heart disease prevention
•  Compensation may be available (if applicable)

Study Details: 

Location: Jacksonville, FL 

All study- related care is provided at no cost to you or your insurance company.

NOVO NN9490-8266 HFpEF HFmrEF (ELS) POLARIS

Purpose of the Study:

This study is testing a new medication called NNC0487-0111 to see if it can safely help people with certain types of heart failure (HFpEF or HFmrEF) who also have excess body weight.

You may qualify if you:

• Have HFpEF or HFmrEF (a type of heart failure).
• Have a BMI of 30 or higher.
• Have stable heart failure symptoms.
• If you have type 2 diabetes, you were diagnosed at least 30 days ago.

You may not qualify if you:

• Had a recent heart attack, stroke, or worsening heart failure.
• Have certain serious heart or lung conditions.
• Have type 1 diabetes.
• Have significant diabetes-related eye disease.
• Have poorly controlled diabetes (HbA1c greater than 10%).

A study team member will review your medical history to determine if the study is right for you.

Why participate?

• Help advance research in heart disease prevention
•  Compensation may be available (if applicable)

Study Details: 

Location: Jacksonville, FL 

All study- related care is provided at no cost to you or your insurance company.