Below is the study criteria information publicly available from Clinicaltrials.gov

• • • 18 Years to 70 Years (Adult, Older Adult)
    • Diagnosis of HeFH or premature CAD

• • • Homozygous familial hypercholesterolemia
    • Active or history of chronic liver disease
    • Current treatment with PCSK9 inhibitor or prior treatment within specified timeframe
    • Clinically significant or abnormal laboratory values as defined by the protocol

About this Study:

This study is evaluating an investigational treatment aimed at lowering the risk of heart disease in individuals with high Lipoprotein(a) [Lp(a)] and other risk factors. You may be eligible if you have elevated levels of this genetic cholesterol marker.

You may qualify if you:

• Are 50 years of age or older

• Have high Lp(a) levels (≥200 nmol/L)
• Have risk factors for heart disease such as:

• High blood pressure

• • Diabetes
  • High cholesterol
  • Smoking history
• Or have evidence of plaque buildup in your arteries

 You may not qualify if you have:

• A prior heart attack, stroke, or TIA

• Had stents, bypass surgery, or plan to have one soon
• A history of major bleeding disorders

Why participate?

• Help advance research in heart disease prevention

• Compensation may be available (if applicable)

Study Details: 

Location: Jacksonville, FL 

All study- related care is provided at no cost to you or your insurance company.

About this Study:

The study  is designed to test whether a specific drug targeting Lp can reduce the risk of first major cardiovascular (CV) events.

You may qualify if you:

• Age ≥50 years
• Elevated (Lipoprotein (a)) Lp(a) during screening
• Multiple atherosclerotic cardiovascular disease risk factors, and/or evidence of atherosclerosis

 You may not qualify if you have:

• Prior acute atherothrombotic event (myocardial infarction, stroke, transient ischemic attack, acute limb ischemia)
• Prior or planned arterial revascularization
• History of major bleeding disorder

Why participate?

• Help advance research in heart disease prevention

• Compensation may be available (if applicable)

Study Details: 

Location: Jacksonville, FL 

All study- related care is provided at no cost to you or your insurance company.

You may qualify if:

• You are 40 years or older

• You have high lipoprotein(a) [Lp(a)]  -done at screening visit
• You have a higher risk of heart disease, such as:

• Coronary artery disease (CAD)

• • Prior stroke
  • Peripheral artery disease
  • Or conditions like familial high cholesterol or type 2 diabetes
• You have been on a stable dose of certain medications for at least 4 weeks, including:

• Cholesterol-lowering medications

• • Hormone-related treatments (such as estrogen, testosterone, etc.)
• Your body mass index (BMI) is between 18.5 and 40

Why participate?

• Help advance research in heart disease prevention

• Compensation may be available (if applicable)

Study Details: 

Location: Jacksonville, FL 

All study- related care is provided at no cost to you or your insurance company.

You may qualify if you:

• Are 18 to 80 years old

• Have been diagnosed with atherosclerotic cardiovascular disease (heart or blood vessel disease caused by plaque buildup)
• Have elevated lipoprotein(a), or Lp(a) — a type of cholesterol in your blood
• Meet other study requirements (the research team will review these with you)

 You may not qualify if you have:

• Have moderate to severe heart failure or your heart is very weak (ejection fraction below 30%)
• Have very high, uncontrolled blood pressure (160+/100+)
• Had serious or uncontrolled heart rhythm problems in the last 3 months
• Had cancer in the past 5 years, except for certain early-stage or treated cancers
• Do not meet other study requirements (the team will review this with you)

Why participate?

• Help advance research in heart disease prevention

• Compensation may be available (if applicable)

Study Details: 

Location: Jacksonville, FL 

All study- related care is provided at no cost to you or your insurance company.

• You may qualify if you:
• Are 18–80 years old

• Have heart/vascular disease (heart attack, stroke, blocked arteries) 
• Have high Lp(a) and LDL >70 mg/dL
• Are on stable cholesterol treatment
• Meet other study requirements (the research team will review these with you)

You may NOT qualify if you:

• Had a recent heart attack, stroke, or surgery

• Have severe heart failure or uncontrolled BP 
• Have serious liver or kidney disease

Recently used certain advanced cholesterol drugs 

• Do not meet other study requirements (the team will review this with you)

Why participate?

• Help advance research in heart disease prevention

• Compensation may be available (if applicable)

Study Details: 

Location: Jacksonville, FL 

All study- related care is provided at no cost to you or your insurance company.