News

GRID VIEW

No more posts
Cirrhosis.jpg

October 17, 2022
Cirrhosis


If you have Cirrhosis you may qualify for one of our studies.

Qualified volunteers may receive at no cost:

  • investigational medication
  • study-related care from a local doctor
  • possible compensation
Health insurance isn’t required to participate.
Ask your doctor or contact our clinic for more information.




    Cirrhosis research is enrolling at:


    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    1.jpg

    April 28, 2020

    Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated disorder. EoE symptoms can overlap with symptoms of a condition called gastroesophageal reflux disease (GERD).

    Patients with EoE experience symptoms described as:

    • feeling like food or liquid is moving slowly
    • feeling food or liquid going down
    • food getting stuck in the esophagus
    • acid reflux, chest pain, nausea, vomiting
    • failure to thrive (children), regurgitation and esophageal strictures.

    It occurs in approximately 1 in 10,000 people and affects people of all age groups, with males being affected more frequently. EOE is associated with food allergies or other allergens, causing eosinophils (type of white blood cell) to migrate from the bone marrow (via blood) and settle in the esophagus causing inflammation to the esophagus. No one knows exactly why EoE occurs.  People with EoE tend to have allergic conditions such asthma, seasonal allergies, allergic rhinitis, and eczema.

    If you are interested in a research study for Eosinophilic Esophagitis, sign up below!

    Qualified volunteers may receive at no cost:

    • investigational medication
    • study-related care from a local doctor
    • possible compensation
    Health insurance isn’t required to participate.
    Ask your doctor or contact our clinic for more information.

    For more information, call one of the offices below.

    Or sign up below and we will contact you!



    • Jacksonville (Borland Groover) Criteria
    Jacksonville (Borland Groover) Criteria

    We are conducting a new clinical trial for people with Eosinophilic Esophagitis (EoE). The clinical trial is investigating tezepelumab – an investigational antibody drug. Tezepelumab has a new and unique action in the body. It stops a chemical produced in the body called thymic stromal lymphopoietin (TSLP). TSLP is increased in some people with EoE and causes inflammation. By blocking TSLP, researchers believe that tezepelumab will reduce inflammation in the esophagus and improve swallowing symptoms for patients with EoE.

    You may be eligible to participate if you:

    • Are 12 – 80 years old
    • Have a diagnosis of EoE confirmed by an upper endoscopy (EGD) and esophageal biopsy
    • Weigh at least 40 kg (88.2 lbs.)
    • Have an average of at least 2 episodes of swallowing difficulties (dysphagia) per week.

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate.

     

    For more information call

    (904) 680-0871

    Or sign up below, and our friendly staff will call you!


    • St. Augustine Criteria
    St. Augustine Criteria

    We are conducting a new clinical trial for people with Eosinophilic Esophagitis (EoE). The clinical trial is investigating tezepelumab – an investigational antibody drug. Tezepelumab has a new and unique action in the body. It stops a chemical produced in the body called thymic stromal lymphopoietin (TSLP). TSLP is increased in some people with EoE and causes inflammation. By blocking TSLP, researchers believe that tezepelumab will reduce inflammation in the esophagus and improve swallowing symptoms for patients with EoE.

    You may be eligible to participate if you:

    • Are 12 – 80 years old
    • Have a diagnosis of EoE confirmed by an upper endoscopy (EGD) and esophageal biopsy
    • Weigh at least 40 kg (88.2 lbs.)
    • Have an average of at least 2 episodes of swallowing difficulties (dysphagia) per week.

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate.

     

    For more information call

    (904) 209-0043

    Or sign up below, and our friendly staff will call you!


    • Inverness Criteria (study #1)
    Inverness Criteria (study #1)

    We are conducting a new clinical trial for people with Eosinophilic Esophagitis (EoE). The clinical trial is investigating tezepelumab – an investigational antibody drug. Tezepelumab has a new and unique action in the body. It stops a chemical produced in the body called thymic stromal lymphopoietin (TSLP). TSLP is increased in some people with EoE and causes inflammation. By blocking TSLP, researchers believe that tezepelumab will reduce inflammation in the esophagus and improve swallowing symptoms for patients with EoE.

    You may be eligible to participate if you:

    • Are 12 – 80 years old
    • Have a diagnosis of EoE confirmed by an upper endoscopy (EGD) and esophageal biopsy
    • Weigh at least 40 kg (88.2 lbs.)
    • Have an average of at least 2 episodes of swallowing difficulties (dysphagia) per week.

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate.

     

    For more information call

    (352) 341-2100

    Or sign up below, and our friendly staff will call you!


    • Inverness Criteria (study #2)
    Inverness Criteria (study #2)

    We are conducting a clinical trial for people who have active EoE.

    This study will evaluate an investigational drug in adults with EoE to see how it reacts with a group of enzymes in the body called CYP (also known as cytochrome P450) that break down drugs.

    The drug-drug interaction study will examine if there are any changes in CYP activity when the study drug and 5 selected approved drugs are given together. The study drug is a biologic agent, called a monoclonal antibody, and will be administered once a week for 17 weeks during the study.

    This study will also evaluate whether the study drug helps the symptoms of EoE, such as trouble swallowing.

    You may be eligible to participate if you:

    • Are 18 – 75 years old
    • Weigh at least 40 kg (88.2 lbs.)
    • Have a diagnosis of eosinophilic esophagitis and active symptoms
    • Are willing and able to receive weekly injections
    • Used or are using proton-pump inhibitor medications but still have symptoms (these are medications used for EoE, heartburn, or indigestion, such as omeprazole [Prilosec], lansoprazole [Prevacid], esomeprazole [Nexium])

    Volunteers must be able to complete some overnight stays at our clinic for this study. There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost. Study participants receive payment for each study visit they attend to reimburse for their time.  No health insurance is required to participate.

     For more information call

    (352) 341-2100

    Or sign up below, and our friendly staff will call you!



    Eosinophilic Esophagitis research is enrolling at:


    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    NASH-Fatty-Liver.jpg

    April 28, 2020
    NASH Fatty Liver


    If you have Fatty Liver, NASH or NAFLD, you may qualify for one of our studies.

    Qualified volunteers may receive at no cost:

    • investigational medication
    • study-related care from a local doctor
    • possible compensation
    Health insurance isn’t required to participate.
    Ask your doctor or contact our clinic for more information.


    • What is NASH? A Silent Liver Disease…
    What is NASH? A Silent Liver Disease…

    The liver is the second largest organ in the body.  Its function is to process everything we eat or drink and filter out any harmful substances from the blood.  When there is too much fat in one’s liver, the filtration process is interrupted and can become a health problem.

    It is estimated that 25% of the world has Non-alcoholic Fatty Liver Disease (NAFLD), a precursor to NASH or Non-Alcoholic Steatohepatitis.  NASH is associated with obesity, cardiovascular disease, type 2 diabetes and metabolic syndrome. It is now the most common liver disorder in the United States and the number one reason for liver transplants.

    Starting as Fatty Liver Disease and then progressing to NASH, the buildup of fat in the liver can lead to inflammation of the liver and liver cell damage.   Progression of NASH leads to fibrosis or stiffening of the liver and cirrhosis or scarring of the liver. NAFLD and NASH are both silent diseases with few symptoms even if the diseases progress to cirrhosis.

    Physicians can monitor liver function blood tests as well as abdominal ultrasounds and liver Fibroscans to determine if you are at risk of developing NAFLD and NASH. However, the only way to definitely determine of you have NASH is to perform a liver biopsy.

    The most common treatment for fatty liver disease is weight loss to reduce the fat in the liver. It is estimated that losing up to 3 to 5% of your body weight can help reduce the fat in the liver. Losing 10% of body weight may help reduce inflammation and even fibrosis in the liver. Currently, there are no medications which have been approved to treat fatty liver disease; however, many are in late stage development with promising results.

    To learn more about current clinical trial opportunities for fatty liver disease and NASH, please contact us.



    Fatty Liver, NASH or NAFLD research is enrolling at:


    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Encore logo

    As a proven clinical research organization, we take every precaution to ensure the safety of and maximize the value for our research volunteers. Qualified doctors, nurses and study coordinators on staff provide support and care throughout the research trial. Participation is always voluntary. We appreciate the time and effort that research volunteers bring to this important process.

    Copyright 2023 ENCORE Research Group