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January 6, 2023
human heart


    Click on the drop-down below to see the criteria for each location. 

    Or sign up at the bottom of this page, and our office will call you!


    • Jacksonville Westside Study (MK0616-015)
    • Fleming Island Study (VICTORION-1)
    • St. Augustine Study (MK0616-015)
    • St. Augustine Study (VICTORION-1)
    Jacksonville Westside Study (MK0616-015)

    Fleming Island Study (VICTORION-1)

    Cardiovascular Disease Risk Research

    Is your LDL cholesterol between 70 and 190? If so, you may be at risk for major cardiovascular events even if you are not experiencing heart symptoms. Preventing a heart attack and stroke is the best line of defense. Cardiovascular disease can cause major cardiovascular events including heart attack, stroke, and cardiovascular death. Research on new medications is needed to help prevent major cardiovascular events.

    We are conducting a research study for volunteers that will evaluate an investigational preventative medication for patients with an increased risk of Cardiovascular Disease.

    You may be eligible if you:

    • Are 40-79 years old
    • Have LDL cholesterol levels between 70 and 190 mg/dL
    • Have NOT had a major cardiovascular event such as heart attack or stroke
    • Are at an increased risk of a first major cardiovascular event, defined by one or more of the following:
      • Coronary artery disease (CAD)
      • High coronary artery calcium (CAC) score
      • Elevated Lipoprotein (a) or hsCRP
      • South Asian Ancestry
      • A family member with cardiovascular disease
      • Pregnancy complications (preeclampsia, gestational hypertension, or gestational diabetes)
      • Metabolic syndrome
      • Chronic Inflammatory disorders including rheumatoid arthritis, lupus (SLE), psoriasis (>10% of the body), Crohn’s disease, ulcerative colitis, or HIV/AIDS

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

    For more information call

    (904) 621-0390

    Or sign up below, and our friendly staff will call you!

    St. Augustine Study (MK0616-015)

    St. Augustine Study (VICTORION-1)

    Cardiovascular Disease Risk Research 

     Is your LDL cholesterol between 70 and 190? If so, you may be at risk for major cardiovascular events even if you are not experiencing heart symptoms. Preventing a heart attack and stroke is the best line of defense. Cardiovascular disease can cause major cardiovascular events including heart attack, stroke, and cardiovascular death. Research on new medications is needed to help prevent major cardiovascular events. 

     

    We are conducting a research study for volunteers that will evaluate an investigational preventative medication for patients with an increased risk of Cardiovascular Disease. 

     

    You may be eligible if you:

    • Are 40-79 years old
    • Have LDL cholesterol levels between 70 and 190 mg/dL
    • Have NOT had a major cardiovascular event such as heart attack or stroke
    • Are at an increased risk of a first major cardiovascular event, defined by one or more of the following:
      • Coronary artery disease (CAD)
      • High coronary artery calcium (CAC) score
      • Elevated Lipoprotein (a) or hsCRP
      • South Asian Ancestry
      • A family member with cardiovascular disease
      • Pregnancy complications (preeclampsia, gestational hypertension, or gestational diabetes)
      • Metabolic syndrome
      • Chronic Inflammatory disorders including rheumatoid arthritis, lupus (SLE), psoriasis (>10% of the body), Crohn’s disease, ulcerative colitis, or HIV/AIDS

     

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate. 

    For more information call
    (904) 209-0043
    Or sign up below, and our friendly staff will call you! 



    This research study is enrolling at:


    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Heart-and-Heart-beat.jpg

    July 12, 2023
    Heart-and-Heart-beat


      If you or someone you know is at risk for heart attack or stoke, call us today! We have multiple cardiovascular and cholesterol research studies enrolling now.

      No cost, and no health insurance is required to participate.
      Ask your doctor or contact our clinic for more information.

      Call: (904) 730-0166


      This research study is enrolling at:


      Jacksonville Center for Clinical Research
      4085 University Blvd., South, Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      BELOW ARE HIDDEN ROWS

      Fleming Island Center for Clinical Research
      1679 Eagle Harbor Parkway
      Suite D, 2nd Floor Fleming Island, FL 32003
      (904) 621-0390



      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      Nature Coast Clinical Research – Crystal River
      6122 West Corporate Oaks Drive
      Crystal River, FL 34429
      (352) 861-1865



      Learn More

      If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


      cholesterol-2.jpg

      January 30, 2020

      If you or someone you know has High Cholesterol, call us today! We have research studies enrolling now.

      Click on the drop-down below to see the criteria for each location. 

      Or sign up at the bottom of this page, and our office will call you!



      • Fleming Island Study (VICTORION-1)
      • Inverness Study #1 (Pursuit)
      • Jacksonville Study #1 (Pursuit)
      • Jacksonville Westside (MK0616-015)
      • St. Augustine Study (VICTORION-1)
      • St. Augustine (MK0616-015)
      Fleming Island Study (VICTORION-1)

      Cardiovascular Disease Risk Research

      Is your LDL cholesterol between 70 and 190? If so, you may be at risk for major cardiovascular events even if you are not experiencing heart symptoms. Preventing a heart attack and stroke is the best line of defense. Cardiovascular disease can cause major cardiovascular events including heart attack, stroke, and cardiovascular death. Research on new medications is needed to help prevent major cardiovascular events.

      We are conducting a research study for volunteers that will evaluate an investigational preventative medication for patients with an increased risk of Cardiovascular Disease.

      You may be eligible if you:

      • Are 40-79 years old
      • Have LDL cholesterol levels between 70 and 190 mg/dL
      • Have NOT had a major cardiovascular event such as heart attack or stroke
      • Are at an increased risk of a first major cardiovascular event, defined by one or more of the following:
        • Coronary artery disease (CAD)
        • High coronary artery calcium (CAC) score
        • Elevated Lipoprotein (a) or hsCRP
        • South Asian Ancestry
        • A family member with cardiovascular disease
        • Pregnancy complications (preeclampsia, gestational hypertension, or gestational diabetes)
        • Metabolic syndrome
        • Chronic Inflammatory disorders including rheumatoid arthritis, lupus (SLE), psoriasis (>10% of the body), Crohn’s disease, ulcerative colitis, or HIV/AIDS

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

      For more information call

      (904) 621-0390

      Or sign up below, and our friendly staff will call you!

      Inverness Study #1 (Pursuit)

      High LDL Cholesterol Research 

      Dyslipidemia is one of the major risks for the leading cause of mortality worldwide, cardiovascular disease. Dyslipidemia means abnormal levels of fats (lipids) in the blood. Extra fats in the blood can accumulate in the arteries, increasing the risk of heart disease, heart attack, and stroke. A particularly dangerous type of fat is low-density lipoprotein cholesterol, often abbreviated to LDL-C. Statins have traditionally been the go-to medication to treat high cholesterol, but some patients continue to have persistently high LDL-C despite taking these medications. Some researchers hope to fight high cholesterol using a new class of medication called PCSK9 inhibitors that may help the body break down LDL-C and reduce cholesterol levels. 

       

      Nature Coast Clinical Research – Inverness is conducting a research study to evaluate a new investigational PCSK9 inhibitor medication for dyslipidemia. 

       

      You may be eligible to participate if you: 

      • Are 18-75 years old 
      • Have high LDL-C Cholesterol (70-189) 
      • Are on daily moderate or high-dose statin therapy 
        • Atorvastatin 10+ mg 
        • Lovastatin 40+ mg 
        • Pravastatin 40+ mg 
        • Rosuvastatin 5+ mg 
        • Simvastatin 40+ mg 

       

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for study-related time and travel. No health insurance is required to participate. 

       

      For more information call 

      (352) 341-2100 

      Or sign up below, and our friendly staff will call you! 

      Jacksonville Study #1 (Pursuit)

      High LDL Cholesterol Research 

      Dyslipidemia is one of the major risks for the leading cause of mortality worldwide, cardiovascular disease. Dyslipidemia means abnormal levels of fats (lipids) in the blood. Extra fats in the blood can accumulate in the arteries, increasing the risk of heart disease, heart attack, and stroke. A particularly dangerous type of fat is low-density lipoprotein cholesterol, often abbreviated to LDL-C. Statins have traditionally been the go-to medication to treat high cholesterol, but some patients continue to have persistently high LDL-C despite taking these medications. Some researchers hope to fight high cholesterol using a new class of medication called PCSK9 inhibitors that may help the body break down LDL-C and reduce cholesterol levels. 

       

      Jacksonville Center for Clinical Research is conducting a research study to evaluate a new investigational PCSK9 inhibitor medication for dyslipidemia. 

       

      You may be eligible to participate if you: 

      • Are 18-75 years old 
      • Have high LDL-C Cholesterol (70-189) 
      • Are on daily moderate or high-dose statin therapy 
        • Atorvastatin 10+ mg 
        • Lovastatin 40+ mg 
        • Pravastatin 40+ mg 
        • Rosuvastatin 5+ mg 
        • Simvastatin 40+ mg 

       

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for study-related time and travel. No health insurance is required to participate. 

       

      For more information call 

      (904) 730-0166 

      Or sign up below, and our friendly staff will call you! 

      Jacksonville Westside (MK0616-015)

      St. Augustine Study (VICTORION-1)

      Cardiovascular Disease Risk Research 

       Is your LDL cholesterol between 70 and 190? If so, you may be at risk for major cardiovascular events even if you are not experiencing heart symptoms. Preventing a heart attack and stroke is the best line of defense. Cardiovascular disease can cause major cardiovascular events including heart attack, stroke, and cardiovascular death. Research on new medications is needed to help prevent major cardiovascular events. 

       

      We are conducting a research study for volunteers that will evaluate an investigational preventative medication for patients with an increased risk of Cardiovascular Disease. 

       

      You may be eligible if you:

      • Are 40-79 years old
      • Have LDL cholesterol levels between 70 and 190 mg/dL
      • Have NOT had a major cardiovascular event such as heart attack or stroke
      • Are at an increased risk of a first major cardiovascular event, defined by one or more of the following:
        • Coronary artery disease (CAD)
        • High coronary artery calcium (CAC) score
        • Elevated Lipoprotein (a) or hsCRP
        • South Asian Ancestry
        • A family member with cardiovascular disease
        • Pregnancy complications (preeclampsia, gestational hypertension, or gestational diabetes)
        • Metabolic syndrome
        • Chronic Inflammatory disorders including rheumatoid arthritis, lupus (SLE), psoriasis (>10% of the body), Crohn’s disease, ulcerative colitis, or HIV/AIDS

       

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate. 

      For more information call
      (904) 209-0043
      Or sign up below, and our friendly staff will call you! 

      St. Augustine (MK0616-015)



      Cholesterol research is enrolling at:


      Fleming Island Center for Clinical Research
      1679 Eagle Harbor Parkway
      Suite D, 2nd Floor Fleming Island, FL 32003
      (904) 621-0390



      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      BELOW ARE HIDDEN ROWS

      Fleming Island Center for Clinical Research
      1679 Eagle Harbor Parkway
      Suite D, 2nd Floor Fleming Island, FL 32003
      (904) 621-0390



      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      Nature Coast Clinical Research – Crystal River
      6122 West Corporate Oaks Drive
      Crystal River, FL 34429
      (352) 861-1865



      Learn More

      If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


      Weight-Loss-1.jpg

      July 27, 2022


      Click on the drop-down below to see the criteria for each location. 

      Or sign up at the bottom of this page, and our office will call you!


      • Crystal River – Study (SYNCHRONIZE)
      • Jacksonville Westside – Study (SYNCHRONIZE)
      • Jacksonville (University)- Study (SUSTAIN OPTIMIZE)
      • Jacksonville (University) – Study (REVITALIZE)
      • Inverness – Study (ACHIEVE 4)
      Crystal River – Study (SYNCHRONIZE)

      Overweight With Other Conditions

      Nature Coast Clinical Research – Crystal River is conducting a research study that will evaluate the effect of an investigational weight loss drug on cardiovascular safety in people who are overweight or obese.

      Obesity is widespread, difficult to manage, and can be unhealthy. It can increase cardiovascular risks, including chances of stroke, heart attack, and high blood pressure. Multiple signals in the body may change with obesity, making weight loss difficult. Medications that target these signaling pathways are needed to help fight this increasing epidemic, and clinical trials are needed to investigate potential solutions.

      You may be eligible to participate if you:

      • Are 18+ years old
      • Have a BMI >27 with any of the following (A and/or B)
        • A. Have Cardiovascular Disease (CVD), including any of the following:
            • Heart failure
            • Coronary artery disease (CAD)
            • Previous heart attack
            • Previous stroke (ischemic or hemorrhagic)
            • Previous revascularization procedure
            • Stent(s)
            • Peripheral artery disease
        • B. Have a BMI >30 with Chronic Kidney Disease (CKD)

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost. Compensation for time and travel may be available. No health insurance is required to participate.

      For more information call

      (352) 563-1865

      Or sign up below, and our friendly staff will call you!

      Jacksonville Westside – Study (SYNCHRONIZE)

      Overweight With Other Conditions

      Westside Center for Clinical Research is conducting a research study that will evaluate the effect of an investigational weight loss drug on cardiovascular safety in people who are overweight or obese.

      Obesity is widespread, difficult to manage, and can be unhealthy. It can increase cardiovascular risks, including chances of stroke, heart attack, and high blood pressure. Multiple signals in the body may change with obesity, making weight loss difficult. Medications that target these signaling pathways are needed to help fight this increasing epidemic, and clinical trials are needed to investigate potential solutions.

      You may be eligible to participate if you:

      • Are 18+ years old
      • Have a BMI >27 with any of the following (A and/or B)
        • A. Have Cardiovascular Disease (CVD), including any of the following:
            • Heart failure
            • Coronary artery disease (CAD)
            • Previous heart attack
            • Previous stroke (ischemic or hemorrhagic)
            • Previous revascularization procedure
            • Stent(s)
            • Peripheral artery disease
        • B. Have a BMI >30 with Chronic Kidney Disease (CKD)

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost. Compensation for time and travel may be available. No health insurance is required to participate.

      For more information call

      (904) 693-1490

      Or sign up below, and our friendly staff will call you!

      Jacksonville (University)- Study (SUSTAIN OPTIMIZE)

      Diabetes Research

      We are conducting a research study for people with type 2 diabetes who are currently taking insulin glargine (ex: Lantus Solostar) and metformin. This research study will evaluate the effectiveness and safety of using semaglutide once weekly as an add-on treatment.

      You may be eligible if you:

      • Are 18 or older
      • Are diagnosed with type 2 diabetes
      • Have a BMI of 25 or greater
      • Are taking daily metformin ≥1500 mg or maximally tolerated dose
      • Are taking once-daily insulin glargine (ex: Lantus Solostar) < 40 units per day

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive all study-related investigational drug, procedures, and medical exams at no cost, as well as a stipend for time and travel. No health insurance is required to participate.

      For more information call

      (904) 730-0166

      Or sign up below, and our office will call you!

      Jacksonville (University) – Study (REVITALIZE)
      Inverness – Study (ACHIEVE 4)

      Type 2 Diabetes and Increased Risk for Heart Disease or Stroke

      Type 2 diabetes is frequently associated with coexisting conditions such as increased weight, hypertension, and increased blood lipoprotein (fat/cholesterol) concentrations. People with type 2 diabetes have a higher risk for cardiovascular disease. Global studies show approximately a third of individuals with type 2 diabetes have cardiovascular disease.

      We are conducting a research study that will be comparing a new investigational medication with insulin therapy for people with type 2 diabetes and excess weight who are at risk for heart disease or stroke.

      You may be eligible if you:

      • Are at least 18 years of age
      • Have a BMI of 25 or higher
      • Have type 2 diabetes with an HbA1c between 7 and 10.5
      • Are taking at least one oral medication for diabetes
      • Have or are at risk for heart disease, stroke, or other blood vessel diseases, or have kidney disease

      There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

      For more information call

      (352) 341-2100

      Or sign up below, and our friendly staff will call you!



      This research is enrolling at:


      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      Nature Coast Clinical Research – Crystal River
      6122 West Corporate Oaks Drive
      Crystal River, FL 34429
      (352) 563-1865



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      BELOW ARE HIDDEN ROWS

      Fleming Island Center for Clinical Research
      1679 Eagle Harbor Parkway
      Suite D, 2nd Floor Fleming Island, FL 32003
      (904) 621-0390



      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      Nature Coast Clinical Research – Crystal River
      6122 West Corporate Oaks Drive
      Crystal River, FL 34429
      (352) 861-1865



      Learn More

      If you want us to contact you about this research study call (904) 730-0166 or sign up below!


      Encore logo

      As a proven clinical research organization, we take every precaution to ensure the safety of and maximize the value for our research volunteers. Qualified doctors, nurses and study coordinators on staff provide support and care throughout the research trial. Participation is always voluntary. We appreciate the time and effort that research volunteers bring to this important process.

      Copyright 2023 ENCORE Research Group