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COPD.jpg

May 31, 2024


If you or someone you know has COPD, you may qualify for one of our research studies.

Qualified volunteers may receive the following at no cost:

  • investigational medication
  • study-related care from a local doctor
  • possible compensation
Health insurance isn’t required to participate.
Ask your doctor or contact our clinic for more information.
Or sign up below, and we will contact you!


  • Fleming Island
  • Jacksonville Borland Groover
  • Jacksonville University Blvd.
  • Jacksonville Westside
  • Nature Coast – Crystal River
  • Nature Coast – Inverness
  • St. Augustine
Fleming Island
Jacksonville Borland Groover
Jacksonville University Blvd.
Jacksonville Westside
Nature Coast – Crystal River
Nature Coast – Inverness
St. Augustine


This research study is enrolling at:


Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865




Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway
Suite D, 2nd Floor Fleming Island, FL 32003
(904) 621-0390



Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086

(904) 209-0043



ENCORE Borland Groover Clinical Research
4800 Belfort Road, Suite 301
Jacksonville, FL 32256
(904) 680-0871



Westside Center for Clinical Research
810 Lane Avenue South
Jacksonville, FL 32205
(904) 693-1490



Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865



Learn More

If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


blepharitis-ad.jpg

July 5, 2024

  • Nature Coast – Crystal River
Nature Coast – Crystal River

Blepharitis (Inflamed Eyelid) Research

Blepharitis is an inflammation of the eyelid that can be caused by bacteria, parasites, problems with the eyelid’s glands, or other associated conditions. Symptoms of blepharitis include eye discomfort and crusting on eyelashes. It can affect people of all ages and backgrounds. Unfortunately, there are currently no FDA approved medications available for most types of blepharitis, though accurate diagnosis and good eyelid hygiene are the first steps.

Nature Coast Clinical Research – Crystal River is conducting a research study that will evaluate an investigational ointment for treating blepharitis (eyelid inflammation).

You may be eligible to participate if you:

  • Have an inflamed eyelid (blepharitis)
  • Have had blepharitis in the past that did not respond adequately to lid hygiene

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related investigational ointment, eyelid wipes, & medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate.

For more information call

(352) 563-1865

Or sign up below, and our friendly staff will call you!



  • Fleming Island
  • Jacksonville Borland Groover
  • Jacksonville University Blvd.
  • Jacksonville Westside
  • Nature Coast – Crystal River
  • Nature Coast – Inverness
  • St. Augustine
Fleming Island
Jacksonville Borland Groover
Jacksonville University Blvd.
Jacksonville Westside
Nature Coast – Crystal River
Nature Coast – Inverness
St. Augustine


This research study is enrolling at:


Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 563-1865



Learn More

If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


Volunteers.jpg

April 28, 2020


    If you are a healthy volunteer interested in research, you may qualify for one of our studies.
    Healthy Volunteer Study Opportunities:
    • Vaccine Studies
      • COVID-19
      • Influenza
      • RSV
      • Norovirus
    Qualified volunteers may receive at no cost:
    • investigational medication
    • study-related care from a local doctor
    • possible compensation
    Health insurance isn’t required to participate.
    Ask your doctor or contact our clinic for more information
    (904) 730-0166
    Or sign up below!


    • Fleming Island
    • Jacksonville Borland Groover
    • Jacksonville University Blvd.
    • Jacksonville Westside
    • Nature Coast – Crystal River
    • Nature Coast – Inverness
    • St. Augustine
    Fleming Island
    Jacksonville Borland Groover
    Jacksonville University Blvd.
    Jacksonville Westside
    Nature Coast – Crystal River
    Nature Coast – Inverness
    St. Augustine


    This research study is enrolling at:


    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Heart-Failure.jpg

    July 22, 2021
    Heart Failure

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. 


    For more information, call:

    (904) 730-0166 (Jacksonville)
    (904) 209-0043 (St. Augustine)
    (352) 563-1865 (Crystal River)
    (352) 341-2100 (Inverness)

    Click on the drop-down below to see the criteria for each location. 

    Or sign up below, and our office will call you!


    • Crystal River – Study (HERMES)
    • Inverness – Study (R2R)
    • Inverness – Study (Reduced EF)
    • Jacksonville: University Blvd – Study (HERMES)
    • Jacksonville: University Blvd – Study (Reduced EF)
    • Jacksonville: University Blvd – Study (R2R)
    • St. Augustine – Study (HERMES)
    • St. Augustine – Study (Athena)
    Crystal River – Study (HERMES)

    Heart Failure Clinical Research

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

    You may be eligible if you:

    • Are 18 or older
    • Have heart failure
    • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

    For more information call

    (352) 341-2100

    Or sign up below, and our friendly staff will call you!

    Inverness – Study (R2R)

    Worsening Heart Failure Research 

    Are you or someone you know currently experiencing swelling in the legs or feet due to worsening heart failure? If you need an increase in your diuretics to address your symptoms, you may be eligible to participate in our heart failure clinical research study.  

    Nature Coast Clinical Research – Inverness is conducting a research study that will evaluate an investigational medication for people with Worsening Heart Failure. 

    You may be eligible to participate if you:

    • Are 18+ years old 
    • Are currently taking heart failure medication 
    • Have been hospitalized for heart failure within the past 12 months  
    • Need an increase in your diuretics (oral or IV) 
    • Have at least two of the following symptoms of worsening heart failure congestion:  
      • Dyspnea (Difficult or labored breathing)  
      • Orthopnea (shortness of breath that occurs while lying flat and is relieved by sitting or standing)  
      • Fatigue (a feeling of constant exhaustion, burnout or lack of energy)  
      • Jugular venous distention (when the vein that runs down the right side of the neck is swollen)  
      • Rales (Small clicking, bubbling, or rattling sounds in the lungs)  
      • Edema (swelling caused by too much fluid trapped in the body’s tissues) 

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate. 

     For more information call 

    (352) 341-2100 

    Or sign up below, and our friendly staff will call you! 

    Inverness – Study (Reduced EF)

    Heart Failure Research

    With heart failure, the heart becomes incapable of pumping enough blood to meet the needs of the entire body. This condition affects millions of Americans and can limit how much ordinary physical activity people can perform. Despite long-term trends, recent data shows that the rate of heart failure is on the rise for many Americans. Clinical research is needed to address this growing concern. 

    Nature Coast Clinical Research – Inverness is conducting a research study for volunteers to evaluate an investigational medication for people with Heart Failure and a reduced ejection fraction. 

     You may be eligible to participate if you: 

    • Are 18+ years old 
    • Have symptoms of heart failure 
      • Shortness of breath 
      • Fatigue 
      • Chest pain 
    • Have an Ejection Fraction (LVEF) less than 50% 
    • Have been on stable ACE inhibitor, ARB medication, or Entresto for at least 1 month 

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate. 

    For more information call 

    (352) 341-2100

    Or sign up below, and our friendly staff will call you!

    Jacksonville: University Blvd – Study (HERMES)

    Heart Failure Clinical Research

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life.

    Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

    You may be eligible if you:

    • Are 18 or older
    • Have heart failure
    • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate.

     For more information call

    (904) 730-0166

    Or sign up below, and our friendly staff will call you!

    Jacksonville: University Blvd – Study (Reduced EF)

    Heart Failure Research

    With heart failure, the heart becomes incapable of pumping enough blood to meet the needs of the entire body. This condition affects millions of Americans and can limit how much ordinary physical activity people can perform. Despite long-term trends, recent data shows that the rate of heart failure is on the rise for many Americans. Clinical research is needed to address this growing concern. 

    Jacksonville Center for Clinical Research is conducting a research study for volunteers to evaluate an investigational medication for people with Heart Failure and a reduced ejection fraction. 

     You may be eligible to participate if you: 

    • Are 18+ years old 
    • Have symptoms of heart failure 
      • Shortness of breath 
      • Fatigue 
      • Chest pain 
    • Have an Ejection Fraction (LVEF) less than 50% 
    • Have been on stable ACE inhibitor, ARB medication, or Entresto for at least 1 month 

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate. 

    For more information call 

    (904) 730-0166

    Or sign up below, and our friendly staff will call you!

    Jacksonville: University Blvd – Study (R2R)

    Worsening Heart Failure Research 

    Are you or someone you know currently experiencing swelling in the legs or feet due to worsening heart failure? If you need an increase in your diuretics to address your symptoms, you may be eligible to participate in our heart failure clinical research study.  

    Jacksonville Center for Clinical Research is conducting a research study that will evaluate an investigational medication for people with Worsening Heart Failure. 

    You may be eligible to participate if you:

    • Are 18+ years old 
    • Are currently taking heart failure medication 
    • Have been hospitalized for heart failure within the past 12 months  
    • Need an increase in your diuretics (oral or IV) 
    • Have at least two of the following symptoms of worsening heart failure congestion:  
      • Dyspnea (Difficult or labored breathing)  
      • Orthopnea (shortness of breath that occurs while lying flat and is relieved by sitting or standing)  
      • Fatigue (a feeling of constant exhaustion, burnout or lack of energy)  
      • Jugular venous distention (when the vein that runs down the right side of the neck is swollen)  
      • Rales (Small clicking, bubbling, or rattling sounds in the lungs)  
      • Edema (swelling caused by too much fluid trapped in the body’s tissues) 

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate. 

     For more information call 

    (904) 730-0166 

    Or sign up below, and our friendly staff will call you! 

    St. Augustine – Study (HERMES)

    Heart Failure Clinical Research

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

    You may be eligible if you:

    • Are 18 or older
    • Have heart failure
    • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

    For more information call

    (904) 209-0043

    Or sign up below, and our friendly staff will call you!

    St. Augustine – Study (Athena)

    Heart Failure Clinical Research

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

    You may be eligible if you:

    • Are 18 or older
    • Have heart failure
    • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

    For more information call

    (904) 209-0043

    Or sign up below, and our friendly staff will call you!



    This research is enrolling at:


    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    cholesterol-heart.jpg

    January 30, 2020
    cholesterol heart


    If you or someone you know has heart disease, call us today! We have multiple cardiovascular research studies enrolling now.

    No cost, and no health insurance is required to participate.
    Ask your doctor or contact our clinic for more information.

    For more information call:
    (904) 730-0166
    Or sign up below!



    • Fleming Island
    • Jacksonville Borland Groover
    • Jacksonville University Blvd.
    • Jacksonville Westside
    • Nature Coast – Crystal River
    • Nature Coast – Inverness
    • St. Augustine
    Fleming Island
    Jacksonville Borland Groover
    Jacksonville University Blvd.
    Jacksonville Westside
    Nature Coast – Crystal River
    Nature Coast – Inverness
    St. Augustine


    Heart Disease research is enrolling at:


    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    Nature Coast Clinical Research
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Blood-Pressure.jpg

    June 1, 2021
    Blood Pressure Research

    Click on the drop-down below to see the criteria for each location. 

    Or sign up at the bottom of this page, and our office will call you!


    • Crystal River – Study (Pacemaker – Backbeat)
    Crystal River – Study (Pacemaker – Backbeat)

    For Clinicaltrials.gov information, click here.

    For more information call
    (352) 563-1865

    Or sign up below, and our friendly staff will call you!



    High Blood Pressure research is enrolling at:


    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Encore logo

    As a proven clinical research organization, we take every precaution to ensure the safety of and maximize the value for our research volunteers. Qualified doctors, nurses and study coordinators on staff provide support and care throughout the research trial. Participation is always voluntary. We appreciate the time and effort that research volunteers bring to this important process.

    Copyright 2023 ENCORE Research Group