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Glaucoma-eye-drops.jpg

April 28, 2020
Glaucoma eye drops

If you or someone you know has Glaucoma, call us about research studies.

No cost, and no health insurance is required to participate.
Ask your doctor or contact our clinic for more information.

For more information call:
(352) 563-1865
Or sign up below!



This research study is enrolling at:


Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 563-1865



Learn More

If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


Heart-stethoscope.jpg

May 4, 2022


If you or someone you know has heart failure, call us today! We have multiple cardiovascular research studies enrolling now.

No cost, and no health insurance is required to participate.
Ask your doctor or contact our clinic for more information.

For more information call:
(904) 730-0166
Or sign up below!



This research is enrolling at:


Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 563-1865



St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086

(904) 209-0043



Learn More

If you want us to contact you about this research study call (904) 730-0166 or sign up below!


Sciatica-2.png

November 17, 2023

Click on the drop-down below to see the criteria for each location. 

Or sign up at the bottom of this page, and our office will call you!



  • Fleming Island Study
  • Jacksonville Study
  • Nature Coast Crystal River Study
Fleming Island Study

Painful Lumbosacral Radiculopathy (Sciatica) 

 Painful lumbosacral radiculopathy, commonly known as sciatica, is a specific kind of low back pain due to inflammation or pinching of a spinal nerve. It presents as electric, burning, and/or sharp pain in the lower back which may radiate into the legs. Researchers are currently investigating a method of targeting lumbosacral radiculopathy pain by preventing peripheral nerves from sending pain signals.   

 

Fleming Island Center for Clinical Research is conducting a research study that will evaluate an investigational medication for Painful Lumbosacral Radiculopathy (sciatica). 

 

You may be eligible to participate if you: 

  • Are 18-70 years old 
  • Are over 100 pounds with a BMI under 40 
  • Have been diagnosed with painful lumbosacral radiculopathy (sciatica) for at least 3 months; with leg pain worse than back pain 
  • Have not used opioids for chronic pain in the last 3 months or taken opioids for more than 7 days for acute pain in the past 3 months. 

 

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with compensation for study-related time and reimbursement for travel. No health insurance is required to participate. 

For more information call 

(904) 621-0390 

Or sign up below, and our friendly staff will call you! 

Jacksonville Study

Painful Lumbosacral Radiculopathy (Sciatica) 

 Painful lumbosacral radiculopathy, commonly known as sciatica, is a specific kind of low back pain due to inflammation or pinching of a spinal nerve. It presents as electric, burning, and/or sharp pain in the lower back which may radiate into the legs. Researchers are currently investigating a method of targeting lumbosacral radiculopathy pain by preventing peripheral nerves from sending pain signals.   

 

Jacksonville Center for Clinical Research is conducting a research study that will evaluate an investigational medication for Painful Lumbosacral Radiculopathy (sciatica). 

 

You may be eligible to participate if you: 

  • Are 18-70 years old 
  • Are over 100 pounds with a BMI under 40 
  • Have been diagnosed with painful lumbosacral radiculopathy (sciatica) for at least 3 months; with leg pain worse than back pain 
  • Have not used opioids for chronic pain in the last 3 months or taken opioids for more than 7 days for acute pain in the past 3 months. 

 

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with compensation for study-related time and reimbursement for travel. No health insurance is required to participate. 

 

For more information call 

(904) 730-0166 

Or sign up below, and our friendly staff will call you! 

Nature Coast Crystal River Study

 Painful Lumbosacral Radiculopathy (Sciatica) 

Painful lumbosacral radiculopathy, commonly known as sciatica, is a specific kind of low back pain due to inflammation or pinching of a spinal nerve. It presents as electric, burning, and/or sharp pain in the lower back which may radiate into the legs. Researchers are currently investigating a method of targeting lumbosacral radiculopathy pain by preventing peripheral nerves from sending pain signals.   

 

Nature Coast Clinical Research – Crystal River is conducting a research study that will evaluate an investigational medication for Painful Lumbosacral Radiculopathy (sciatica). 

 

You may be eligible to participate if you: 

  • Are 18-70 years old 
  • Are over 100 pounds with a BMI under 40 
  • Have been diagnosed with painful lumbosacral radiculopathy (sciatica) for at least 3 months; with leg pain worse than back pain 
  • Have not used opioids for chronic pain in the last 3 months or taken opioids for more than 7 days for acute pain in the past 3 months. 

 

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with compensation for study-related time and reimbursement for travel. No health insurance is required to participate. 

 

For more information call 

(352) 563-1865 

Or sign up below, and our friendly staff will call you! 




    Lumbosacral Radiculopathy research is enrolling at:


    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    cactus.gout_.jpg

    August 11, 2023

    Gout is a painful and progressive form of arthritis. It is caused by a buildup of uric acid, which crystalizes inside of joints. This leads to inflammation, immune response, pain, and joint damage.


    Click on the drop-down below to see the criteria for each location. 

    Or sign up at the bottom of this page, and our office will call you!



    • Jacksonville Gout Study
    • Crystal River Gout Study
    Jacksonville Gout Study

    Gout is a painful and progressive form of arthritis. It is caused by a buildup of uric acid, which crystalizes inside of joints. This leads to inflammation, immune response, pain, and joint damage.

    We are conducting a clinical research study for people who have gout. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication for gout.

    You may be eligible if you:

    • Are 19 to 69 years old
    • Have been diagnosed with gout
    • Have a BMI of 18 to 40
    • Do not have rheumatoid arthritis or another autoimmune disease

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

    For more information call

    (904) 730-0166

    Crystal River Gout Study

    Gout is a painful and progressive form of arthritis. It is caused by a buildup of uric acid, which crystalizes inside of joints. This leads to inflammation, immune response, pain, and joint damage.

    We are conducting a clinical research study for people who have gout. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication for gout.

    You may be eligible if you:

    • Are 19 to 69 years old
    • Have been diagnosed with gout
    • Have a BMI of 18 to 40
    • Do not have rheumatoid arthritis or another autoimmune disease

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

    For more information call

    (352) 563-1865



    Gout research is enrolling at:


    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Heart-Failure.jpg

    July 22, 2021

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. 


    For more information, call:

    (904) 730-0166 (Jacksonville)
    (904) 209-0043 (St. Augustine)
    (352) 563-1865 (Crystal River)
    (352) 341-2100 (Inverness)

    Click on the drop-down below to see the criteria for each location. 

    Or sign up below, and our office will call you!


    • Jacksonville – Study (HERMES)
    • Jacksonville – Study (R2R)
    • St. Augustine – Study (HERMES)
    • Crystal River – Study (HERMES)
    • Inverness – Study (R2R)
    Jacksonville – Study (HERMES)

    Heart Failure Clinical Research

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life.

    Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

    You may be eligible if you:

    • Are 18 or older
    • Have heart failure
    • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate.

     For more information call

    (904) 730-0166

    Or sign up below, and our friendly staff will call you!

    Jacksonville – Study (R2R)

    Worsening Heart Failure Research 

    Are you or someone you know currently experiencing swelling in the legs or feet due to worsening heart failure? If you need an increase in your diuretics to address your symptoms, you may be eligible to participate in our heart failure clinical research study.  

    Jacksonville Center for Clinical Research is conducting a research study that will evaluate an investigational medication for people with Worsening Heart Failure. 

    You may be eligible to participate if you:

    • Are 18+ years old 
    • Are currently taking heart failure medication 
    • Have been hospitalized for heart failure within the past 12 months  
    • Need an increase in your diuretics (oral or IV) 
    • Have at least two of the following symptoms of worsening heart failure congestion:  
      • Dyspnea (Difficult or labored breathing)  
      • Orthopnea (shortness of breath that occurs while lying flat and is relieved by sitting or standing)  
      • Fatigue (a feeling of constant exhaustion, burnout or lack of energy)  
      • Jugular venous distention (when the vein that runs down the right side of the neck is swollen)  
      • Rales (Small clicking, bubbling, or rattling sounds in the lungs)  
      • Edema (swelling caused by too much fluid trapped in the body’s tissues) 

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate. 

     For more information call 

    (904) 730-0166 

    Or sign up below, and our friendly staff will call you! 

    St. Augustine – Study (HERMES)

    Heart Failure Clinical Research

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

    You may be eligible if you:

    • Are 18 or older
    • Have heart failure
    • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

    For more information call

    (904) 209-0043

    Or sign up below, and our friendly staff will call you!

    Crystal River – Study (HERMES)

    Heart Failure Clinical Research

    Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

    You may be eligible if you:

    • Are 18 or older
    • Have heart failure
    • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

    For more information call

    (352) 341-2100

    Or sign up below, and our friendly staff will call you!

    Inverness – Study (R2R)

    Worsening Heart Failure Research 

    Are you or someone you know currently experiencing swelling in the legs or feet due to worsening heart failure? If you need an increase in your diuretics to address your symptoms, you may be eligible to participate in our heart failure clinical research study.  

    Nature Coast Clinical Research – Inverness is conducting a research study that will evaluate an investigational medication for people with Worsening Heart Failure. 

    You may be eligible to participate if you:

    • Are 18+ years old 
    • Are currently taking heart failure medication 
    • Have been hospitalized for heart failure within the past 12 months  
    • Need an increase in your diuretics (oral or IV) 
    • Have at least two of the following symptoms of worsening heart failure congestion:  
      • Dyspnea (Difficult or labored breathing)  
      • Orthopnea (shortness of breath that occurs while lying flat and is relieved by sitting or standing)  
      • Fatigue (a feeling of constant exhaustion, burnout or lack of energy)  
      • Jugular venous distention (when the vein that runs down the right side of the neck is swollen)  
      • Rales (Small clicking, bubbling, or rattling sounds in the lungs)  
      • Edema (swelling caused by too much fluid trapped in the body’s tissues) 

    There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate. 

     For more information call 

    (352) 341-2100 

    Or sign up below, and our friendly staff will call you! 



    This research is enrolling at:


    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    cholesterol-heart.jpg

    January 30, 2020
    cholesterol heart


    If you or someone you know has heart disease, call us today! We have multiple cardiovascular research studies enrolling now.

    No cost, and no health insurance is required to participate.
    Ask your doctor or contact our clinic for more information.

    For more information call:
    (904) 730-0166
    Or sign up below!



    Heart Disease research is enrolling at:


    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    Nature Coast Clinical Research
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Blood-Pressure.jpg

    June 1, 2021
    Blood Pressure Research

    Click on the drop-down below to see the criteria for each location. 

    Or sign up at the bottom of this page, and our office will call you!


    • Crystal River Study (Pacemaker – Backbeat)
    Crystal River Study (Pacemaker – Backbeat)

    For Clinicaltrials.gov information, click here.

    For more information call
    (352) 563-1865

    Or sign up below, and our friendly staff will call you!



    High Blood Pressure research is enrolling at:


    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 563-1865



    BELOW ARE HIDDEN ROWS

    Fleming Island Center for Clinical Research
    1679 Eagle Harbor Parkway
    Suite D, 2nd Floor Fleming Island, FL 32003
    (904) 621-0390



    Jacksonville Center for Clinical Research
    4085 University Blvd., South
    Suite 1
    Jacksonville, FL 32216
    (904) 730-0166



    St. Johns Center for Clinical Research
    100 Whetstone Place,
    Suites 300 – 301,
    St. Augustine, FL 32086

    (904) 209-0043



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Westside Center for Clinical Research
    810 Lane Avenue South
    Jacksonville, FL 32205
    (904) 693-1490



    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    Nature Coast Clinical Research – Crystal River
    6122 West Corporate Oaks Drive
    Crystal River, FL 34429
    (352) 861-1865



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    red-eye.jpg

    March 23, 2021
    red eye


      If you or someone you know has Keratitis, call us today! We have research studies enrolling now.

      No cost, and no health insurance is required to participate.
      Ask your doctor or contact our clinic for more information.

      For more information call:
      (352) 563-1865
      Or sign up below!




        This research study is enrolling at:


        Nature Coast Clinical Research – Crystal River
        6122 West Corporate Oaks Drive
        Crystal River, FL 34429
        (352) 563-1865



        Learn More

        If you want us to contact you about our research studies call (904) 730-0166 or sign up below!

        No Fields Found.

        Presbyopia-1.jpg

        July 20, 2021


          If you or someone you know has Presbyopia, call us today! We have research studies enrolling now.

          Symptoms of Presbyopia:

          • Difficulty reading small print
          • Having to hold reading material farther away
          • Headaches
          • Eyestrain

          Click on the drop-down below to see the criteria for each location. 

          Or sign up at the bottom of this page, and our office will call you!


          • Crystal River Study (VT)
          Crystal River Study (VT)

          Presbyopia Research Study

          Do you find yourself holding your phone or books further away to see clearly? It could be presbyopia!

          Presbyopia is the gradual loss of ability to focus on nearby objects. Symptoms include blurred vision, eye strain, and headache after reading or computer use. Often people become aware of presbyopia when they start holding books and newspapers at arm’s length to be able to read them.  Current therapies for presbyopia include reading glasses, contact lenses or surgery. There is a need for medications that can help treat presbyopia.

          We are conducting a research study that will evaluate an investigational eye drop medication for presbyopia.

          You may be eligible if you:

          • Are 45 – 80 years old
          • Have lens implants in both eyes

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

          For more information call

          (352) 563-1865

          Or sign up below, and our friendly staff will call you!



          This research study is enrolling at:


          Nature Coast Clinical Research – Crystal River
          6122 West Corporate Oaks Drive
          Crystal River, FL 34429
          (352) 563-1865



          Learn More

          If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


          Diabetes-Overweight-1.jpg

          January 5, 2023

          Click on the drop-down below to see the criteria for each location. 

          Or sign up at the bottom of this page, and our office will call you!


          • Jacksonville – Study #1 (SUSTAIN OPTIMIZE)
          • Inverness – Study #1 (ACHIEVE 4)
          Jacksonville – Study #1 (SUSTAIN OPTIMIZE)

          We are conducting a research study for people with type 2 diabetes who are currently taking insulin glargine (ex: Lantus Solostar) and metformin. This research study will evaluate the effectiveness and safety of using semaglutide once weekly as an add-on treatment.

          You may be eligible if you:

          • Are 18 or older
          • Are diagnosed with type 2 diabetes
          • Have a BMI of 25 or greater
          • Are taking daily metformin ≥1500 mg or maximally tolerated dose
          • Are taking once-daily insulin glargine (ex: Lantus Solostar) < 40 units per day

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive all study-related investigational drug, procedures, and medical exams at no cost, as well as a stipend for time and travel. No health insurance is required to participate.

          For more information call

          (904) 730-0166

          Or sign up below, and our office will call you!

          Inverness – Study #1 (ACHIEVE 4)

          Type 2 Diabetes and Increased Risk for Heart Disease or Stroke

          Type 2 diabetes is frequently associated with coexisting conditions such as increased weight, hypertension, and increased blood lipoprotein (fat/cholesterol) concentrations. People with type 2 diabetes have a higher risk for cardiovascular disease. Global studies show approximately a third of individuals with type 2 diabetes have cardiovascular disease.

          We are conducting a research study that will be comparing a new investigational medication with insulin therapy for people with type 2 diabetes and excess weight who are at risk for heart disease or stroke.

          You may be eligible if you:

          • Are at least 18 years of age
          • Have a BMI of 25 or higher
          • Have type 2 diabetes with an HbA1c between 7 and 10.5
          • Are taking at least one oral medication for diabetes
          • Have or are at risk for heart disease, stroke, or other blood vessel diseases, or have kidney disease

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

          For more information call

          (352) 341-2100

          Or sign up below, and our friendly staff will call you!



          This research is enrolling at:


          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          BELOW ARE HIDDEN ROWS

          Fleming Island Center for Clinical Research
          1679 Eagle Harbor Parkway
          Suite D, 2nd Floor Fleming Island, FL 32003
          (904) 621-0390



          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          St. Johns Center for Clinical Research
          100 Whetstone Place,
          Suites 300 – 301,
          St. Augustine, FL 32086

          (904) 209-0043



          ENCORE Borland Groover Clinical Research
          4800 Belfort Road, Suite 301
          Jacksonville, FL 32256
          (904) 680-0871



          Westside Center for Clinical Research
          810 Lane Avenue South
          Jacksonville, FL 32205
          (904) 693-1490



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          Nature Coast Clinical Research – Crystal River
          6122 West Corporate Oaks Drive
          Crystal River, FL 34429
          (352) 861-1865



          Learn More

          If you want us to contact you about this research study call (904) 730-0166 or sign up below!


          Weight-Loss-1.jpg

          July 27, 2022


          Click on the drop-down below to see the criteria for each location. 

          Or sign up at the bottom of this page, and our office will call you!


          • Crystal River – Study (SYNCHRONIZE)
          • Jacksonville Westside – Study (SYNCHRONIZE)
          • Jacksonville (University)- Study (SUSTAIN OPTIMIZE)
          • Jacksonville (University) – Study (REVITALIZE)
          • Inverness – Study (ACHIEVE 4)
          Crystal River – Study (SYNCHRONIZE)

          Overweight With Other Conditions

          Nature Coast Clinical Research – Crystal River is conducting a research study that will evaluate the effect of an investigational weight loss drug on cardiovascular safety in people who are overweight or obese.

          Obesity is widespread, difficult to manage, and can be unhealthy. It can increase cardiovascular risks, including chances of stroke, heart attack, and high blood pressure. Multiple signals in the body may change with obesity, making weight loss difficult. Medications that target these signaling pathways are needed to help fight this increasing epidemic, and clinical trials are needed to investigate potential solutions.

          You may be eligible to participate if you:

          • Are 18+ years old
          • Have a BMI >27 with any of the following (A and/or B)
            • A. Have Cardiovascular Disease (CVD), including any of the following:
                • Heart failure
                • Coronary artery disease (CAD)
                • Previous heart attack
                • Previous stroke (ischemic or hemorrhagic)
                • Previous revascularization procedure
                • Stent(s)
                • Peripheral artery disease
            • B. Have a BMI >30 with Chronic Kidney Disease (CKD)

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost. Compensation for time and travel may be available. No health insurance is required to participate.

          For more information call

          (352) 563-1865

          Or sign up below, and our friendly staff will call you!

          Jacksonville Westside – Study (SYNCHRONIZE)

          Overweight With Other Conditions

          Westside Center for Clinical Research is conducting a research study that will evaluate the effect of an investigational weight loss drug on cardiovascular safety in people who are overweight or obese.

          Obesity is widespread, difficult to manage, and can be unhealthy. It can increase cardiovascular risks, including chances of stroke, heart attack, and high blood pressure. Multiple signals in the body may change with obesity, making weight loss difficult. Medications that target these signaling pathways are needed to help fight this increasing epidemic, and clinical trials are needed to investigate potential solutions.

          You may be eligible to participate if you:

          • Are 18+ years old
          • Have a BMI >27 with any of the following (A and/or B)
            • A. Have Cardiovascular Disease (CVD), including any of the following:
                • Heart failure
                • Coronary artery disease (CAD)
                • Previous heart attack
                • Previous stroke (ischemic or hemorrhagic)
                • Previous revascularization procedure
                • Stent(s)
                • Peripheral artery disease
            • B. Have a BMI >30 with Chronic Kidney Disease (CKD)

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost. Compensation for time and travel may be available. No health insurance is required to participate.

          For more information call

          (904) 693-1490

          Or sign up below, and our friendly staff will call you!

          Jacksonville (University)- Study (SUSTAIN OPTIMIZE)

          Diabetes Research

          We are conducting a research study for people with type 2 diabetes who are currently taking insulin glargine (ex: Lantus Solostar) and metformin. This research study will evaluate the effectiveness and safety of using semaglutide once weekly as an add-on treatment.

          You may be eligible if you:

          • Are 18 or older
          • Are diagnosed with type 2 diabetes
          • Have a BMI of 25 or greater
          • Are taking daily metformin ≥1500 mg or maximally tolerated dose
          • Are taking once-daily insulin glargine (ex: Lantus Solostar) < 40 units per day

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive all study-related investigational drug, procedures, and medical exams at no cost, as well as a stipend for time and travel. No health insurance is required to participate.

          For more information call

          (904) 730-0166

          Or sign up below, and our office will call you!

          Jacksonville (University) – Study (REVITALIZE)
          Inverness – Study (ACHIEVE 4)

          Type 2 Diabetes and Increased Risk for Heart Disease or Stroke

          Type 2 diabetes is frequently associated with coexisting conditions such as increased weight, hypertension, and increased blood lipoprotein (fat/cholesterol) concentrations. People with type 2 diabetes have a higher risk for cardiovascular disease. Global studies show approximately a third of individuals with type 2 diabetes have cardiovascular disease.

          We are conducting a research study that will be comparing a new investigational medication with insulin therapy for people with type 2 diabetes and excess weight who are at risk for heart disease or stroke.

          You may be eligible if you:

          • Are at least 18 years of age
          • Have a BMI of 25 or higher
          • Have type 2 diabetes with an HbA1c between 7 and 10.5
          • Are taking at least one oral medication for diabetes
          • Have or are at risk for heart disease, stroke, or other blood vessel diseases, or have kidney disease

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate.

          For more information call

          (352) 341-2100

          Or sign up below, and our friendly staff will call you!



          This research is enrolling at:


          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          Westside Center for Clinical Research
          810 Lane Avenue South
          Jacksonville, FL 32205
          (904) 693-1490



          Nature Coast Clinical Research – Crystal River
          6122 West Corporate Oaks Drive
          Crystal River, FL 34429
          (352) 563-1865



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          BELOW ARE HIDDEN ROWS

          Fleming Island Center for Clinical Research
          1679 Eagle Harbor Parkway
          Suite D, 2nd Floor Fleming Island, FL 32003
          (904) 621-0390



          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          St. Johns Center for Clinical Research
          100 Whetstone Place,
          Suites 300 – 301,
          St. Augustine, FL 32086

          (904) 209-0043



          ENCORE Borland Groover Clinical Research
          4800 Belfort Road, Suite 301
          Jacksonville, FL 32256
          (904) 680-0871



          Westside Center for Clinical Research
          810 Lane Avenue South
          Jacksonville, FL 32205
          (904) 693-1490



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          Nature Coast Clinical Research – Crystal River
          6122 West Corporate Oaks Drive
          Crystal River, FL 34429
          (352) 861-1865



          Learn More

          If you want us to contact you about this research study call (904) 730-0166 or sign up below!


          Encore logo

          As a proven clinical research organization, we take every precaution to ensure the safety of and maximize the value for our research volunteers. Qualified doctors, nurses and study coordinators on staff provide support and care throughout the research trial. Participation is always voluntary. We appreciate the time and effort that research volunteers bring to this important process.

          Copyright 2023 ENCORE Research Group