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hs-CRP.jpg

October 16, 2024

If you have an hs-CRP >2, type 2 diabetes, CKD, or had a previous heart attack or stroke, you may qualify for one of our research studies.

Qualified volunteers may receive at no cost:

  • study-related care from a local doctor
  • possible compensation

Health insurance isn’t required to participate.
Ask your doctor or contact our clinic for more information.

Or sign up below and we will contact you!




  • Fleming Island
  • Jacksonville Borland Groover
  • Jacksonville University Blvd.
  • Jacksonville Westside
  • Nature Coast – Crystal River
  • Nature Coast – Inverness
  • St. Augustine
Fleming Island
Jacksonville Borland Groover
Jacksonville University Blvd.
Jacksonville Westside
Nature Coast – Crystal River
Nature Coast – Inverness
St. Augustine


This research study is enrolling at:


Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway
Suite D, 2nd Floor Fleming Island, FL 32003
(904) 621-0390



Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086

(904) 209-0043



ENCORE Borland Groover Clinical Research
4800 Belfort Road, Suite 301
Jacksonville, FL 32256
(904) 680-0871



Westside Center for Clinical Research
810 Lane Avenue South
Jacksonville, FL 32205
(904) 693-1490



Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865



Learn More

If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


Norovirus-Research.jpg

August 15, 2024

Norovirus is a highly contagious virus that is the leading cause of acute gastroenteritis (stomach bug) and foodborne illness in the U.S., striking people of all ages with sudden bouts of severe nausea, vomiting, stomach pain, and diarrhea.

Norovirus remains a formidable public health challenge, causing millions of cases of acute gastroenteritis annually. Despite its widespread impact, there is currently no approved vaccine to prevent acute gastroenteritis caused by the norovirus. To combat this persistent virus clinical trials are imperative to develop an effective norovirus prevention vaccine.

ENCORE Research Group is conducting a Phase 3 clinical research study to evaluate the effectiveness and safety of an investigational vaccine to prevent norovirus acute gastroenteritis.

You may be eligible to participate if you:

  • Are 18 or older
  • Do NOT have a diagnosis of chronic symptomatic gastrointestinal disease, including IBS, colitis, esophageal reflux, or any other medical condition that is associated with symptoms of regular vomiting or diarrhea
  • Are NOT currently pregnant or breastfeeding

There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related investigational vaccines, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate.

For more information call

904-730-0166

Or sign up below, and our friendly staff will call you!



  • Fleming Island
  • Jacksonville Borland Groover
  • Jacksonville University Blvd.
  • Jacksonville Westside
  • Nature Coast – Crystal River
  • Nature Coast – Inverness
  • St. Augustine
Fleming Island
Jacksonville Borland Groover
Jacksonville University Blvd.
Jacksonville Westside
Nature Coast – Crystal River
Nature Coast – Inverness
St. Augustine


This research study is enrolling at:


Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086

(904) 209-0043



Westside Center for Clinical Research
810 Lane Avenue South
Jacksonville, FL 32205
(904) 693-1490



Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway
Suite D, 2nd Floor Fleming Island, FL 32003
(904) 621-0390



Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086

(904) 209-0043



ENCORE Borland Groover Clinical Research
4800 Belfort Road, Suite 301
Jacksonville, FL 32256
(904) 680-0871



Westside Center for Clinical Research
810 Lane Avenue South
Jacksonville, FL 32205
(904) 693-1490



Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865



Learn More

If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


polycystic-kidney-disease.jpg

August 15, 2024


If you or someone you know has Polycystic Kidney Disease, you may qualify for one of our research studies.

Qualified volunteers may receive the following at no cost:

  • investigational medication (if applicable)
  • study-related care from a local doctor
  • possible compensation

Health insurance isn’t required to participate.
Ask your doctor or contact our clinic for more information.

Or sign up below, and we will contact you!



  • Fleming Island
  • Jacksonville Borland Groover
  • Jacksonville University Blvd.
  • Jacksonville Westside
  • Nature Coast – Crystal River
  • Nature Coast – Inverness
  • St. Augustine
Fleming Island
Jacksonville Borland Groover
Jacksonville University Blvd.
Jacksonville Westside
Nature Coast – Crystal River
Nature Coast – Inverness
St. Augustine


This research study is enrolling at:


Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway
Suite D, 2nd Floor Fleming Island, FL 32003
(904) 621-0390



Jacksonville Center for Clinical Research
4085 University Blvd., South
Suite 1
Jacksonville, FL 32216
(904) 730-0166



St. Johns Center for Clinical Research
100 Whetstone Place,
Suites 300 – 301,
St. Augustine, FL 32086

(904) 209-0043



ENCORE Borland Groover Clinical Research
4800 Belfort Road, Suite 301
Jacksonville, FL 32256
(904) 680-0871



Westside Center for Clinical Research
810 Lane Avenue South
Jacksonville, FL 32205
(904) 693-1490



Nature Coast Clinical Research – Inverness
411 West Highland Boulevard
Inverness, FL 34452
(352) 341-2100



Nature Coast Clinical Research – Crystal River
6122 West Corporate Oaks Drive
Crystal River, FL 34429
(352) 861-1865



Learn More

If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


Cirrhosis.jpg

October 17, 2022
Cirrhosis


If you have Cirrhosis you may qualify for one of our studies.

Qualified volunteers may receive at no cost:

  • investigational medication
  • study-related care from a local doctor
  • possible compensation
Health insurance isn’t required to participate.
Ask your doctor or contact our clinic for more information.


  • Fleming Island
  • Jacksonville Borland Groover
  • Jacksonville University Blvd.
  • Jacksonville Westside
  • Nature Coast – Crystal River
  • Nature Coast – Inverness
  • St. Augustine
Fleming Island
Jacksonville Borland Groover
Jacksonville University Blvd.
Jacksonville Westside
Nature Coast – Crystal River
Nature Coast – Inverness
St. Augustine




    Cirrhosis research is enrolling at:


    Nature Coast Clinical Research – Inverness
    411 West Highland Boulevard
    Inverness, FL 34452
    (352) 341-2100



    ENCORE Borland Groover Clinical Research
    4800 Belfort Road, Suite 301
    Jacksonville, FL 32256
    (904) 680-0871



    Learn More

    If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


    Gastroparesis-2.jpg

    August 1, 2023
    Gastroparesis


    If you are interested in a research study for Diabetic Gastroparesis, sign up below!

    Qualified volunteers may receive at no cost:

    • investigational medication
    • study-related care from a local doctor
    • possible compensation
    Health insurance isn’t required to participate.
    Ask your doctor or contact our clinic for more information.


    • Fleming Island
    • Jacksonville Borland Groover
    • Jacksonville University Blvd.
    • Jacksonville Westside
    • Nature Coast – Crystal River
    • Nature Coast – Inverness
    • St. Augustine
    Fleming Island
    Jacksonville Borland Groover
    Jacksonville University Blvd.
    Jacksonville Westside
    Nature Coast – Crystal River
    Nature Coast – Inverness
    St. Augustine




      Diabetic Gastroparesis research is enrolling at:


      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      BELOW ARE HIDDEN ROWS

      Fleming Island Center for Clinical Research
      1679 Eagle Harbor Parkway
      Suite D, 2nd Floor Fleming Island, FL 32003
      (904) 621-0390



      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      Nature Coast Clinical Research – Crystal River
      6122 West Corporate Oaks Drive
      Crystal River, FL 34429
      (352) 861-1865



      Learn More

      If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


      Crohns-Disease-2.jpg

      April 28, 2020
      Crohn's Disease

      If you have Crohn’s Disease, you may qualify for one of our research studies.

      Qualified volunteers may receive at no cost:

      • investigational medication
      • study-related care from a local doctor
      • possible compensation
      Health insurance isn’t required to participate.
      Ask your doctor or contact our clinic for more information.


      • Fleming Island
      • Jacksonville Borland Groover
      • Jacksonville University Blvd.
      • Jacksonville Westside
      • Nature Coast – Crystal River
      • Nature Coast – Inverness
      • St. Augustine
      Fleming Island
      Jacksonville Borland Groover
      Jacksonville University Blvd.
      Jacksonville Westside
      Nature Coast – Crystal River
      Nature Coast – Inverness
      St. Augustine


      Crohn’s Disease research is enrolling at:


      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      Learn More

      If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


      1.jpg

      April 28, 2020

      Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated disorder. EoE symptoms can overlap with symptoms of a condition called gastroesophageal reflux disease (GERD).

      Patients with EoE experience symptoms described as:

      • feeling like food or liquid is moving slowly
      • feeling food or liquid going down
      • food getting stuck in the esophagus
      • acid reflux, chest pain, nausea, vomiting
      • failure to thrive (children), regurgitation and esophageal strictures.

      It occurs in approximately 1 in 10,000 people and affects people of all age groups, with males being affected more frequently. EOE is associated with food allergies or other allergens, causing eosinophils (type of white blood cell) to migrate from the bone marrow (via blood) and settle in the esophagus causing inflammation to the esophagus. No one knows exactly why EoE occurs.  People with EoE tend to have allergic conditions such asthma, seasonal allergies, allergic rhinitis, and eczema.


      Click on the drop-down below to see the criteria for each location. 

      Or sign up at the bottom of this page, and our office will call you!



      • Fleming Island
      • Jacksonville Borland Groover
      • Jacksonville University Blvd.
      • Jacksonville Westside
      • Nature Coast – Crystal River
      • Nature Coast – Inverness
      • St. Augustine
      Fleming Island
      Jacksonville Borland Groover
      Jacksonville University Blvd.
      Jacksonville Westside
      Nature Coast – Crystal River
      Nature Coast – Inverness
      St. Augustine

      • Inverness – Study (ALAMERE)
      Inverness – Study (ALAMERE)


      • Jacksonville: Borland Groover – Study (ALAMERE)
      Jacksonville: Borland Groover – Study (ALAMERE)




      Eosinophilic Esophagitis research is enrolling at:


      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      BELOW ARE HIDDEN ROWS

      Fleming Island Center for Clinical Research
      1679 Eagle Harbor Parkway
      Suite D, 2nd Floor Fleming Island, FL 32003
      (904) 621-0390



      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      Nature Coast Clinical Research – Crystal River
      6122 West Corporate Oaks Drive
      Crystal River, FL 34429
      (352) 861-1865



      Learn More

      If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


      NASH-Fatty-Liver.jpg

      April 28, 2020
      NASH Fatty Liver

      If you have NASH/MASH or NAFLD/MASLD, you may qualify for one of our research studies.

      Qualified volunteers may receive at no cost:

      • investigational medication

      • study-related care from a local doctor

      • possible compensation

      Health insurance isn’t required to participate.
      Ask your doctor or contact our clinic for more information.

      Or sign up below and we will contact you!



      • Fleming Island
      • Jacksonville Borland Groover
      • Jacksonville University Blvd.
      • Jacksonville Westside
      • Nature Coast – Crystal River
      • Nature Coast – Inverness
      • St. Augustine
      Fleming Island
      Jacksonville Borland Groover
      Jacksonville University Blvd.
      Jacksonville Westside
      Nature Coast – Crystal River
      Nature Coast – Inverness
      St. Augustine


      • Inverness – Study (SYNCHRONY)
      • Inverness – Study – Nonalcoholic Steatohepatitis (NASH) Research
      • Inverness – Study – Non-Invasively Diagnosed NASH/MASH and NAFLD/MASLD
      • Jacksonville Borland Groover – Study – Non-Invasively Diagnosed NASH/MASH and NAFLD/MASLD
      • Jacksonville Borland Groover – Study (SYNCHRONY)
      Inverness – Study (SYNCHRONY)

      Inverness – Study – Nonalcoholic Steatohepatitis (NASH) Research

      Nonalcoholic Steatohepatitis (NASH) Research

      Nonalcoholic Steatohepatitis (NASH) is a progressive fatty liver disease which can lead to serious health complications, including cirrhosis, liver disease, liver cancer, and death. NASH is inflammation in the liver caused by excess fat. It disrupts liver function. There are currently no approved treatments available for NASH. Therefore, clinical trials are needed to explore new treatment options.

      We are conducting a research study for volunteers that will evaluate an investigational medication for Nonalcoholic Steatohepatitis (NASH).

      You may be eligible if you:

      • Are at least 18 years old
      • Have NASH
      • Do not have cirrhosis or other chronic liver diseases
      • Do not have type 1 diabetes

      There are additional criteria to meet to qualify for this study. Study participation is voluntary and free of charge. A stipend for time and travel will be provided. No health insurance is required to participate.

      For more information call
      (352) 341-2100
      Or sign up below, and our friendly staff will call you!

      Inverness – Study – Non-Invasively Diagnosed NASH/MASH and NAFLD/MASLD

      Non-Invasively Diagnosed NASH/MASH and NAFLD/MASLD

      If you have  NASH/MASH or NAFLD/MASLD, you may qualify for one of our research studies.

      Qualified volunteers may receive at no cost:

      • investigational medication
      • study-related care from a local doctor
      • possible compensation

      Health insurance isn’t required to participate.
      Ask your doctor or contact our clinic for more information.

      Or sign up below and we will contact you!

      Study Information below is from Clinicaltrials.gov

      Inclusion Criteria:

      Main Study Only:

      • Males and non-pregnant, non-lactating females between 18 – 80 (between 19-80 in the Republic of Korea) years of age inclusive, on the day of signing informed consent

      • Previous history or presence of 2 out of 4 components of metabolic syndrome (obesity, dyslipidemia, elevated blood pressure, elevated fasting glucose) or type 2 diabetes

      • Suspected or confirmed diagnosis of NASH/MASH or NAFLD/MASLD or non-invasively diagnosed NASH/MASH or NAFLD/MASLD

      Open-Label Rollover

      • Prior participation in the placebo arm of a previous Akero Phase 2 study

      Exclusion Criteria:

      • Other causes of liver disease based on medical history and/or liver histology and/or central laboratory results, including but not limited to: alcoholic liver disease, autoimmune disorders (e.g., primary biliary cholangitis [PBC], primary sclerosing cholangitis [PSC], autoimmune hepatitis), drug induced hepatotoxicity, Wilson disease, clinically significant iron overload, or alpha-1-antitrypsin deficiency

      • Type 1 or unstable Type 2 diabetes

      A reduced list of inclusion and exclusion criteria apply to participants in the open-label rollover extension.

      Other inclusion and exclusion criteria may apply.

      Jacksonville Borland Groover – Study – Non-Invasively Diagnosed NASH/MASH and NAFLD/MASLD

      Non-Invasively Diagnosed NASH/MASH and NAFLD/MASLD

      If you have  NASH/MASH or NAFLD/MASLD, you may qualify for one of our research studies.

      Qualified volunteers may receive at no cost:

      • investigational medication
      • study-related care from a local doctor
      • possible compensation

      Health insurance isn’t required to participate.
      Ask your doctor or contact our clinic for more information.

      Or sign up below and we will contact you!

      Study Information below is from Clinicaltrials.gov

      Inclusion Criteria:

      Main Study Only:

      • Males and non-pregnant, non-lactating females between 18 – 80 (between 19-80 in the Republic of Korea) years of age inclusive, on the day of signing informed consent

      • Previous history or presence of 2 out of 4 components of metabolic syndrome (obesity, dyslipidemia, elevated blood pressure, elevated fasting glucose) or type 2 diabetes

      • Suspected or confirmed diagnosis of NASH/MASH or NAFLD/MASLD or non-invasively diagnosed NASH/MASH or NAFLD/MASLD

      Open-Label Rollover

      • Prior participation in the placebo arm of a previous Akero Phase 2 study

      Exclusion Criteria:

      • Other causes of liver disease based on medical history and/or liver histology and/or central laboratory results, including but not limited to: alcoholic liver disease, autoimmune disorders (e.g., primary biliary cholangitis [PBC], primary sclerosing cholangitis [PSC], autoimmune hepatitis), drug induced hepatotoxicity, Wilson disease, clinically significant iron overload, or alpha-1-antitrypsin deficiency

      • Type 1 or unstable Type 2 diabetes

      A reduced list of inclusion and exclusion criteria apply to participants in the open-label rollover extension.

      Other inclusion and exclusion criteria may apply.

      Jacksonville Borland Groover – Study (SYNCHRONY)



      Fatty Liver, NASH or NAFLD research is enrolling at:


      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      BELOW ARE HIDDEN ROWS

      Fleming Island Center for Clinical Research
      1679 Eagle Harbor Parkway
      Suite D, 2nd Floor Fleming Island, FL 32003
      (904) 621-0390



      Jacksonville Center for Clinical Research
      4085 University Blvd., South
      Suite 1
      Jacksonville, FL 32216
      (904) 730-0166



      St. Johns Center for Clinical Research
      100 Whetstone Place,
      Suites 300 – 301,
      St. Augustine, FL 32086

      (904) 209-0043



      ENCORE Borland Groover Clinical Research
      4800 Belfort Road, Suite 301
      Jacksonville, FL 32256
      (904) 680-0871



      Westside Center for Clinical Research
      810 Lane Avenue South
      Jacksonville, FL 32205
      (904) 693-1490



      Nature Coast Clinical Research – Inverness
      411 West Highland Boulevard
      Inverness, FL 34452
      (352) 341-2100



      Nature Coast Clinical Research – Crystal River
      6122 West Corporate Oaks Drive
      Crystal River, FL 34429
      (352) 861-1865



      Learn More

      If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


      Volunteers.jpg

      April 28, 2020


        If you are a healthy volunteer interested in research, you may qualify for one of our studies.
        Healthy Volunteer Study Opportunities:
        • Vaccine Studies
          • COVID-19
          • Influenza
          • RSV
          • Norovirus
        Qualified volunteers may receive at no cost:
        • investigational medication
        • study-related care from a local doctor
        • possible compensation
        Health insurance isn’t required to participate.
        Ask your doctor or contact our clinic for more information
        (904) 730-0166
        Or sign up below!


        • Fleming Island
        • Jacksonville Borland Groover
        • Jacksonville University Blvd.
        • Jacksonville Westside
        • Nature Coast – Crystal River
        • Nature Coast – Inverness
        • St. Augustine
        Fleming Island
        Jacksonville Borland Groover
        Jacksonville University Blvd.
        Jacksonville Westside
        Nature Coast – Crystal River
        Nature Coast – Inverness
        St. Augustine


        This research study is enrolling at:


        Fleming Island Center for Clinical Research
        1679 Eagle Harbor Parkway
        Suite D, 2nd Floor Fleming Island, FL 32003
        (904) 621-0390



        Jacksonville Center for Clinical Research
        4085 University Blvd., South
        Suite 1
        Jacksonville, FL 32216
        (904) 730-0166



        St. Johns Center for Clinical Research
        100 Whetstone Place,
        Suites 300 – 301,
        St. Augustine, FL 32086

        (904) 209-0043



        Nature Coast Clinical Research – Crystal River
        6122 West Corporate Oaks Drive
        Crystal River, FL 34429
        (352) 861-1865



        Nature Coast Clinical Research – Inverness
        411 West Highland Boulevard
        Inverness, FL 34452
        (352) 341-2100



        Westside Center for Clinical Research
        810 Lane Avenue South
        Jacksonville, FL 32205
        (904) 693-1490



        BELOW ARE HIDDEN ROWS

        Fleming Island Center for Clinical Research
        1679 Eagle Harbor Parkway
        Suite D, 2nd Floor Fleming Island, FL 32003
        (904) 621-0390



        Jacksonville Center for Clinical Research
        4085 University Blvd., South
        Suite 1
        Jacksonville, FL 32216
        (904) 730-0166



        St. Johns Center for Clinical Research
        100 Whetstone Place,
        Suites 300 – 301,
        St. Augustine, FL 32086

        (904) 209-0043



        ENCORE Borland Groover Clinical Research
        4800 Belfort Road, Suite 301
        Jacksonville, FL 32256
        (904) 680-0871



        Westside Center for Clinical Research
        810 Lane Avenue South
        Jacksonville, FL 32205
        (904) 693-1490



        Nature Coast Clinical Research – Inverness
        411 West Highland Boulevard
        Inverness, FL 34452
        (352) 341-2100



        Nature Coast Clinical Research – Crystal River
        6122 West Corporate Oaks Drive
        Crystal River, FL 34429
        (352) 861-1865



        Learn More

        If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


        AdobeStock_326865808-1.jpeg

        September 14, 2023

        If you or someone you know has Chronic Kidney Disease(CKD) and Atherosclerotic Cardiovascular Disease (ASCVD), you may qualify for one of our research studies.

        Qualified volunteers may receive the following at no cost:

        • investigational medication
        • study-related care from a local doctor
        • possible compensation

        Health insurance isn’t required to participate.
        Ask your doctor or contact our clinic for more information.

        Or sign up below, and we will contact you!



        • Jacksonville University Blvd.
        • Nature Coast – Inverness
        Jacksonville University Blvd.

        Join a research study to help find new treatment options for Cardiovascular Disease.

        Basic Criteria:

        • Be 18 years old

        • BMI greater than ≥ 19.0 kg/m2

        • A history of ASCVD defined as myocardial infarction, stroke, or symptomatic peripheral arterial disease, or with risk factors hereof.

        Qualified Participants may receive:
        • Study related care at no cost
        • Study related medical exams at no cost
        • Compensation for time and travel

        Call Jacksonville Center for Clinical Research at 904-379-0742 to see what studies you may qualify for!

        Nature Coast – Inverness

        Join a research study to help find new treatment options for Cardiovascular Disease.

        Basic Criteria:

        • Be 18 years old

        • BMI greater than ≥ 19.0 kg/m2

        • A history of ASCVD defined as myocardial infarction, stroke, or symptomatic peripheral arterial disease, or with risk factors hereof.

        Qualified Participants may receive:
        • Study related care at no cost
        • Study related medical exams at no cost
        • Compensation for time and travel

        Call Nature Coast Clinical Research at (352)-341-2100 to see what studies you may qualify for!





          This research is enrolling at:


          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          BELOW ARE HIDDEN ROWS

          Fleming Island Center for Clinical Research
          1679 Eagle Harbor Parkway
          Suite D, 2nd Floor Fleming Island, FL 32003
          (904) 621-0390



          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          St. Johns Center for Clinical Research
          100 Whetstone Place,
          Suites 300 – 301,
          St. Augustine, FL 32086

          (904) 209-0043



          ENCORE Borland Groover Clinical Research
          4800 Belfort Road, Suite 301
          Jacksonville, FL 32256
          (904) 680-0871



          Westside Center for Clinical Research
          810 Lane Avenue South
          Jacksonville, FL 32205
          (904) 693-1490



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          Nature Coast Clinical Research – Crystal River
          6122 West Corporate Oaks Drive
          Crystal River, FL 34429
          (352) 861-1865



          Learn More

          If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


          Heart-Failure.jpg

          July 22, 2021
          Heart Failure

          Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. 


          For more information, call:

          (904) 730-0166 (Jacksonville)
          (904) 209-0043 (St. Augustine)
          (352) 563-1865 (Crystal River)
          (352) 341-2100 (Inverness)

          Click on the drop-down below to see the criteria for each location. 

          Or sign up below, and our office will call you!


          • Crystal River – Study (HERMES)
          • Inverness – Study (R2R)
          • Inverness – Study (Reduced EF)
          • Jacksonville: University Blvd – Study (HERMES)
          • Jacksonville: University Blvd – Study (Reduced EF)
          • Jacksonville: University Blvd – Study (R2R)
          • St. Augustine – Study (HERMES)
          • St. Augustine – Study (Athena)
          Crystal River – Study (HERMES)

          Heart Failure Clinical Research

          Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

          You may be eligible if you:

          • Are 18 or older
          • Have heart failure
          • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

          For more information call

          (352) 341-2100

          Or sign up below, and our friendly staff will call you!

          Inverness – Study (R2R)

          Worsening Heart Failure Research 

          Are you or someone you know currently experiencing swelling in the legs or feet due to worsening heart failure? If you need an increase in your diuretics to address your symptoms, you may be eligible to participate in our heart failure clinical research study.  

          Nature Coast Clinical Research – Inverness is conducting a research study that will evaluate an investigational medication for people with Worsening Heart Failure. 

          You may be eligible to participate if you:

          • Are 18+ years old 
          • Are currently taking heart failure medication 
          • Have been hospitalized for heart failure within the past 12 months  
          • Need an increase in your diuretics (oral or IV) 
          • Have at least two of the following symptoms of worsening heart failure congestion:  
            • Dyspnea (Difficult or labored breathing)  
            • Orthopnea (shortness of breath that occurs while lying flat and is relieved by sitting or standing)  
            • Fatigue (a feeling of constant exhaustion, burnout or lack of energy)  
            • Jugular venous distention (when the vein that runs down the right side of the neck is swollen)  
            • Rales (Small clicking, bubbling, or rattling sounds in the lungs)  
            • Edema (swelling caused by too much fluid trapped in the body’s tissues) 

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate. 

           For more information call 

          (352) 341-2100 

          Or sign up below, and our friendly staff will call you! 

          Inverness – Study (Reduced EF)

          Heart Failure Research

          With heart failure, the heart becomes incapable of pumping enough blood to meet the needs of the entire body. This condition affects millions of Americans and can limit how much ordinary physical activity people can perform. Despite long-term trends, recent data shows that the rate of heart failure is on the rise for many Americans. Clinical research is needed to address this growing concern. 

          Nature Coast Clinical Research – Inverness is conducting a research study for volunteers to evaluate an investigational medication for people with Heart Failure and a reduced ejection fraction. 

           You may be eligible to participate if you: 

          • Are 18+ years old 
          • Have symptoms of heart failure 
            • Shortness of breath 
            • Fatigue 
            • Chest pain 
          • Have an Ejection Fraction (LVEF) less than 50% 
          • Have been on stable ACE inhibitor, ARB medication, or Entresto for at least 1 month 

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate. 

          For more information call 

          (352) 341-2100

          Or sign up below, and our friendly staff will call you!

          Jacksonville: University Blvd – Study (HERMES)

          Heart Failure Clinical Research

          Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life.

          Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

          You may be eligible if you:

          • Are 18 or older
          • Have heart failure
          • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate.

           For more information call

          (904) 730-0166

          Or sign up below, and our friendly staff will call you!

          Jacksonville: University Blvd – Study (Reduced EF)

          Heart Failure Research

          With heart failure, the heart becomes incapable of pumping enough blood to meet the needs of the entire body. This condition affects millions of Americans and can limit how much ordinary physical activity people can perform. Despite long-term trends, recent data shows that the rate of heart failure is on the rise for many Americans. Clinical research is needed to address this growing concern. 

          Jacksonville Center for Clinical Research is conducting a research study for volunteers to evaluate an investigational medication for people with Heart Failure and a reduced ejection fraction. 

           You may be eligible to participate if you: 

          • Are 18+ years old 
          • Have symptoms of heart failure 
            • Shortness of breath 
            • Fatigue 
            • Chest pain 
          • Have an Ejection Fraction (LVEF) less than 50% 
          • Have been on stable ACE inhibitor, ARB medication, or Entresto for at least 1 month 

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and medical exams at no cost, along with a stipend for time and travel. No health insurance is required to participate. 

          For more information call 

          (904) 730-0166

          Or sign up below, and our friendly staff will call you!

          Jacksonville: University Blvd – Study (R2R)

          Worsening Heart Failure Research 

          Are you or someone you know currently experiencing swelling in the legs or feet due to worsening heart failure? If you need an increase in your diuretics to address your symptoms, you may be eligible to participate in our heart failure clinical research study.  

          Jacksonville Center for Clinical Research is conducting a research study that will evaluate an investigational medication for people with Worsening Heart Failure. 

          You may be eligible to participate if you:

          • Are 18+ years old 
          • Are currently taking heart failure medication 
          • Have been hospitalized for heart failure within the past 12 months  
          • Need an increase in your diuretics (oral or IV) 
          • Have at least two of the following symptoms of worsening heart failure congestion:  
            • Dyspnea (Difficult or labored breathing)  
            • Orthopnea (shortness of breath that occurs while lying flat and is relieved by sitting or standing)  
            • Fatigue (a feeling of constant exhaustion, burnout or lack of energy)  
            • Jugular venous distention (when the vein that runs down the right side of the neck is swollen)  
            • Rales (Small clicking, bubbling, or rattling sounds in the lungs)  
            • Edema (swelling caused by too much fluid trapped in the body’s tissues) 

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate. 

           For more information call 

          (904) 730-0166 

          Or sign up below, and our friendly staff will call you! 

          St. Augustine – Study (HERMES)

          Heart Failure Clinical Research

          Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

          You may be eligible if you:

          • Are 18 or older
          • Have heart failure
          • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

          For more information call

          (904) 209-0043

          Or sign up below, and our friendly staff will call you!

          St. Augustine – Study (Athena)

          Heart Failure Clinical Research

          Heart failure is a serious medical condition where the heart cannot effectively deliver enough oxygenated blood to the organs. It affects millions of Americans and may have debilitating symptoms including edema, shortness of breath, systemic inflammation, and reduced quality of life. Even with the best available treatment, there is still a risk of serious complications. Reducing the amount of systemic inflammation may increase health outcomes for people with heart failure. We are conducting a research study for people with heart failure that will evaluate the effectiveness of an investigational drug on cardiovascular health outcomes.

          You may be eligible if you:

          • Are 18 or older
          • Have heart failure
          • Have a preserved or mildly reduced ejection fraction (LVEF >40%) documented by echocardiography within the past 12 months

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication and study-related medical exams at no cost and a stipend for time and travel. No health insurance is required to participate. 

          For more information call

          (904) 209-0043

          Or sign up below, and our friendly staff will call you!



          This research is enrolling at:


          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          St. Johns Center for Clinical Research
          100 Whetstone Place,
          Suites 300 – 301,
          St. Augustine, FL 32086

          (904) 209-0043



          Nature Coast Clinical Research – Crystal River
          6122 West Corporate Oaks Drive
          Crystal River, FL 34429
          (352) 563-1865



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          BELOW ARE HIDDEN ROWS

          Fleming Island Center for Clinical Research
          1679 Eagle Harbor Parkway
          Suite D, 2nd Floor Fleming Island, FL 32003
          (904) 621-0390



          Jacksonville Center for Clinical Research
          4085 University Blvd., South
          Suite 1
          Jacksonville, FL 32216
          (904) 730-0166



          St. Johns Center for Clinical Research
          100 Whetstone Place,
          Suites 300 – 301,
          St. Augustine, FL 32086

          (904) 209-0043



          ENCORE Borland Groover Clinical Research
          4800 Belfort Road, Suite 301
          Jacksonville, FL 32256
          (904) 680-0871



          Westside Center for Clinical Research
          810 Lane Avenue South
          Jacksonville, FL 32205
          (904) 693-1490



          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          Nature Coast Clinical Research – Crystal River
          6122 West Corporate Oaks Drive
          Crystal River, FL 34429
          (352) 861-1865



          Learn More

          If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


          UC-1.jpg

          December 7, 2019

          Ulcerative colitis (UC) is a painful disease caused by inflammation of the colon. This inflammation causes damage to the mucosal lining of the intestine and can cause damage beneath this protective lining. Unfortunately, many sufferers do not have adequate responses to available medications. Ongoing research into new medications is essential for discovering improved treatments for ulcerative colitis (UC).

          Nature Coast Clinical Research – Inverness is conducting a research study that will evaluate an investigational medication for moderate to severe Ulcerative Colitis.

          You may be eligible to participate if you:

          • Are 16-75 years old
          • Have a diagnosis of ulcerative colitis that is moderate to severely active
          • Have had an inadequate response to 1 or more ulcerative colitis medications:
            • Prednisone
            • Immunomodulators
            • Oral aminosalicylates
            • Advanced therapy

          There are additional criteria to meet to qualify for this study. Volunteers who qualify for our study will receive study-related medication, medical exams at no cost, and a stipend for time and travel. No health insurance is required to participate.

          For more information call

          (352) 341-2100

          Or sign up below, and our friendly staff will call you!



          • Fleming Island
          • Jacksonville Borland Groover
          • Jacksonville University Blvd.
          • Jacksonville Westside
          • Nature Coast – Crystal River
          • Nature Coast – Inverness
          • St. Augustine
          Fleming Island
          Jacksonville Borland Groover
          Jacksonville University Blvd.
          Jacksonville Westside
          Nature Coast – Crystal River
          Nature Coast – Inverness
          St. Augustine


          This research study is enrolling at:


          Nature Coast Clinical Research – Inverness
          411 West Highland Boulevard
          Inverness, FL 34452
          (352) 341-2100



          Learn More

          If you want us to contact you about our research studies call (904) 730-0166 or sign up below!


          Encore logo

          As a proven clinical research organization, we take every precaution to ensure the safety of and maximize the value for our research volunteers. Qualified doctors, nurses and study coordinators on staff provide support and care throughout the research trial. Participation is always voluntary. We appreciate the time and effort that research volunteers bring to this important process.

          Copyright 2023 ENCORE Research Group